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The Parkinson's disease-specific moderating effect of depression on the relationship between sleep and apathy: Insights from dual-cohort moderation analyses
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DOI：10.1016/j.comppsych.2026.152722.png)
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Abstract
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• Depression moderates the sleep-apathy relationship specifically in PD patients. • Sleep latency and behavioral withdrawal are key indicators of this interaction. • Depression may attenuate the association between sleep and apathy severity. • Interaction effects overlap with broader anxiety, fatigue, and motor burden. • Integrated management is needed for co-occurring non-motor symptoms in PD.
Keywords:
Apathy
Depression
Mental health
Parkinson's disease
Sleep disturbance
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