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The prolactin-releasing peptide system: Physiological functions and therapeutic potential in obesity
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DOI：10.1016/j.nbd.2026.107554.png)
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Abstract
En 中文
• Knock-out models reveal critical roles of GPR10 and NPFFR2 in metabolism. • Lipidized PrRP analogs show robust anti-obesity effects in rodents. • Dual GPR10/NPFFR2 signaling mediates anti-obesity effects of PrRP analogs. • PrRP analogs show no yo-yo effect after treatment discontinuation.
Keywords:
Prolactin-releasing peptide
GPR10
NPFFR2
Knock-out mice
Energy homeostasis
Obesity treatment
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5.6
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6.7K
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