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The pursuit of linear dosage in pharmacy: reservoir-based drug delivery systems from macro to micro scale

delete2025-01-09
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PRE
AI
A
Arkady S. Abdurashtov
P
Pavel I. Proshin
G
Gleb B. Sukhorukov *
DOI:10.1080/17425247.2024.2448026delete
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Abstract

Abstract

En 中文
IntroductionThe pursuit of linear dosage in pharmacy is essential for achieving consistent therapeutic release and enhancing patient compliance. This review provides a comprehensive summary of zero-order drug delivery systems, with a particular focus on reservoir-based systems emanated from different microfabrication technologies.Areas coveredThe consideration of recent advances in drug delivery systems is given to encompass the key areas including the importance of achieving a constant drug release rate for therapeutic applications. Detailed examination of reservoir-based systems, their design, mechanisms of action and materials used are highlighted. By addressing these areas, the discussion aims to provide a thorough understanding of most recent zero-order drug delivery systems, their performance advantages and methods of their manufacturing. To ensure the complete coverage of the explored research area, modern AI-assistant tools were used to find not only the most relevant, but also connected and similar articles.Expert opinionFuture developments in reservoir-based drug delivery systems are expected to significantly enhance therapeutic effectiveness and patient outcomes through the integration of innovative materials and technologies. The fabrication of intelligent drug delivery systems that utilize sensors and feedback mechanisms can enable real-time monitoring of drug release and patient reactions.
Keywords:
Drug delivery
reservoir-based systems
polymers
zero-order release
microparticles
films
osmotic pumps
microchips

Journal

Expert Opinion on Drug Delivery cover
Expert Opinion on Drug Delivery
IF:
5.4
Papers:
2.3K
Citations:
1.0W

Organization

No organization information available