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The relationship between objective physical activity and change in cognitive function
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DOI：10.1002/alz.12950.png)
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Abstract
En 中文
IntroductionThe current study investigated the association between objectively measured physical activity and cognition in older adults over approximately 8 years. MethodsWe utilized data from 199 cognitively unimpaired individuals from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study, aged >= 60. Actigraphy was used to measure physical activity (intensity, total activity, and energy expenditure) at baseline. Cognition was assessed using a comprehensive cognitive battery every 18-months. ResultsHigher baseline energy expenditure predicted better episodic recall memory and global cognition over the follow-up period (p = 0.031; p = 0.047, respectively). Those with higher physical activity intensity and greater total activity also had better global cognition over time (both p = 0.005). Finally, higher total physical activity predicted improved episodic recall memory over time (p = 0.022). DiscussionThese results suggest that physical activity can preserve cognition and that activity intensity may play an important role in this association. HighlightsGreater total physical activity predicts preserved episodic memory and global cognition.Moderate intensity physical activity (>3.7 metabolic equivalents of task [MET]) predicts preserved global cognition.Expending > 373 kilocalories per day may benefit episodic memory and global cognition.
Keywords:
aging
Alzheimer's disease
episodic memory
global cognition
longitudinal
physical activity
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11.1
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