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The Role of Apathy in the Association Between Depressive Symptoms and Subjective Cognitive Complaints
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DOI：10.1002/gps.70223.png)
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Abstract
En 中文
Self-perceived cognitive difficulties are a potential early marker of Alzheimer's disease (AD), frequently co-occur with depressive symptoms. This has hindered consideration of these subjective cognitive difficulties as a risk factor for AD. However, accumulating evidence points to dissociations between specific depressive symptoms (i.e., apathy, affective or mood symptoms, and others), with some suggestion that apathy is particularly predictive of and more proximate to AD and may drive the relationship between depressive symptomatology and AD. This study examines whether apathy drives the association between depressive symptoms and subjective cognitive complaints (SCC).
Keywords:
affective symptoms
memory concerns
mood changes
neuropsychiatric symptoms
preclinical Alzheimer's disease
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