arrow
Return

The Serial Coupling-Column Strategy

delete2024-07-17
delete0
PRE
AI
S
Shufang Xu
Y
Yi Yang
J
Jingchun Su
Y
Yu Tian
Y
Yunli Duan
Z
Zhigang Xu
Z
Zhimin Liu *
DOI:10.1080/15422119.2024.2379868delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
It is often difficult to separate and identify complex components using a single column in the different chromatographic techniques. The serial coupling of columns consists in connecting two or more columns with different separation characteristics one after the other, aiming to improve separation performances. The process must simply improve the shortcomings of a specific limited selective performance and low separation degree obtained using a single column in particular cases. Serial coupling must allow for separations that could not be achieved using a single column in these conditions. In this paper, the use of tandem columns in high performance liquid chromatography, gas chromatography, and supercritical fluid chromatography were considered for separations of proteins, metabolites, pharmaceutical, polar compounds, volatile components, chiral enantiomers, lipids, and carotenoids. Problems and requirements encountered coupling columns serially are detailed and solutions are given.
Keywords:
Serial column coupling
high performance liquid chromatography
gas chromatography
supercritical fluid chromatography
chiral separations

Journal

Separation and Purification Reviews cover
Separation and Purification Reviews
IF:
5.6
Papers:
343
Citations:
1.6K

Organization

No organization information available
Cited Papers

Cited Papers

Nonlinear refractive index change of photoactive yellow protein
err1998-10-01
err0
PREAI
errJ. Vanhanen; V.P. Leppanen; T. Haring; V. Kettunen; T. Jaaskelainen; S. Parkkinen; J.P.S. Parkkinen
errShare
errSave
errShare
errSave
errShare
errSave
researcher View more