The survival benefit of postoperative radiotherapy in pN1 head and neck squamous cell carcinoma without adverse pathological features: analysis of the SEER database

Yi Lyu

doi:10.1016/j.oraloncology.2026.108055

The survival benefit of postoperative radiotherapy in pN1 head and neck squamous cell carcinoma without adverse pathological features: analysis of the SEER database

2026-06-24

0

PRE

AI

Y

Yi Lyu

L

Lin Chen

X

Xiaoqing Cen

Y

Yicheng Deng

K

Kexing Lyu

W

Wenbin Lei *

R

Ruihua Fang *

DOI：10.1016/j.oraloncology.2026.108055

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Abstract

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• PORT is associated with improved OS and CSS in pN1, cM0 HNSCC patients without adverse pathological features. • PORT is an independent prognostic factor for OS and CSS. • Patients younger than 60 years old, or with OPSCC/LSCC gain significant survival benefit from PORT in this cohort.

The survival benefit of postoperative radiotherapy in pN1 head and neck squamous cell carcinoma without adverse pathological features: analysis of the SEER database

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