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Therapeutic potential of M2 macrophage-derived exosomes and hyperbaric oxygen in sciatic nerve crush injury: Insights from histological, molecular, and biochemical analyses

delete2026-04-29
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Abdullah A. Alqasem
DOI:10.1016/j.tice.2026.103561delete
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Abstract

Abstract

En 中文
• Combined M2 macrophage-derived exosomes and HBO were evaluated. • The combined therapy improved sciatic nerve histoarchitecture. • Motor functional recovery was enhanced by combined therapy. • Pro-inflammatory cytokines were suppressed after treatment. • Oxidative stress markers were significantly reduced.
Keywords:
M2 macrophage-derived exosomes
hyperbaric oxygen
sciatic nerve injury
neuroprotection
oxidative stress

Journal

Tissue and Cell cover
Tissue and Cell
IF:
2.5
Papers:
867
Citations:
4.1K

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