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Time-Lapse Video-Based Embryo Grading via Complementary Spatial-Temporal Pattern Mining

delete2026-01-01
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PRE
AI
Y
Yong Sun
Y
Yipeng Wang
J
Junyu Shi
Z
Zhiyuan Zhang
Y
Y. L. Xiao
L
Lei Zhu
M
Man‐Xi Jiang *
Q
Qiang Nie *
DOI:10.1007/978-3-032-05169-1_57delete
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Abstract

Abstract

En 中文
Artificial intelligence has recently shown promise in automated embryo selection for In-Vitro Fertilization (IVF). However, current approaches either address partial embryo evaluation lacking holistic quality assessment or target clinical outcomes inevitably confounded by extra-embryonic factors, both limiting clinical utility. To bridge this gap, we propose a new task called Video-Based Embryo Grading the first paradigm that directly utilizes full-length time-lapse monitoring (TLM) videos to predict embryologists' overall quality assessments. To support this task, we curate a real-world clinical dataset comprising over 2,500 TLM videos, each annotated with a grading label indicating the overall quality of embryos. Grounded in clinical decision-making principles, we propose a Complementary Spatial-Temporal Pattern Mining (CoSTeM) framework that conceptually replicates embryologists' evaluation process. The CoSTeM comprises two branches: (1) a morphological branch using a Mixture of Cross-Attentive Experts layer and a Temporal Selection Block to select discriminative local structural features, and (2) a morphokinetic branch employing a Temporal Transformer to model global developmental trajectories, synergistically integrating static and dynamic determinants for grading embryos. Extensive experimental results demonstrate the superiority of our design. This work provides a valuable methodological framework for AI-assisted embryo selection. The source code is available at https://github.com/RIL-Lab/CoSTeM.
Keywords:
Time-lapse Video
In-Vitro Fertilization
Deep Learning

Journal

M
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2025, PT XIII
IF:
0
Papers:
53
Citations:
0

Organization

S
shanghai jiao tong university
Scholars:
15.6W
Papers: 11.6W
Citations: 159