Total NT-proBNP in heart failure with preserved vs reduced ejection fraction

2026-05-09

PRE

Camilla Hage *

Anika Mang

Jean Claude Daubert

Erwan Donal

Peder Myhre

Cecilia Linde

Lars H. Lund

DOI：10.1016/j.ijcard.2026.134554

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Abstract

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• tNT-proBNP is a novel and more accurate measurement of natriuretic peptides detecting also glycosylated parts of the peptide. • Glycosylation of NT-proBNP may be higher in HFpEF than HFrEF. • tNT-proBNP may have superior prognostic ability in HF regardless of LVEF especially in HF populations with high prevalence of glucose perturbations.

Keywords:

tNT-proBNP

heart failure

glycosylation

HFpEF

HFrEF

Total NT-proBNP in heart failure with preserved vs reduced ejection fraction

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