Traceability for protein sequence to function

Amandine Bœuf

doi:10.1038/s41567-025-03130-1

Traceability for protein sequence to function

2026-01-15

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DOI：10.1038/s41567-025-03130-1

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Abstract

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How proteins — sequences of amino acids — fold determines their function. We discuss efforts towards the establishment of metrics traceable to the International System of Units that link the sequence of a protein to its structure and function.

Keywords:

Protein folding

Amino acid sequence

Protein structure

Protein function

Traceability

Traceability for protein sequence to function

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