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Transcription Factor Ets-1 is a Central Regulator of Redox Balance and Liver Regeneration Through EGF and TGF-β1 Signaling

delete2026-06-16
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PRE
AI
Y
Y. H. Kao *
Y
Yu-Chun Lin
T
Tzong-Shyuan Tai
Y
Yao-Chun Hsu
M
Ming-Shian Tsai
P
Po-Han Chen
C
Cheuk-Kwan Sun *
P
Po-Huang Lee *
DOI：10.1016/j.labinv.2026.106146delete
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Abstract

Abstract

En 中文
The transcription factor Ets-1 is widely implicated in hepatic carcinogenesis, yet its precise role in balancing fibrogenesis and regeneration remains poorly defined. This study elucidated the clinical relevance, upstream regulatory mechanisms, and dual cytoprotective/anti-fibrotic functions of Ets-1 during chronic liver injury and repair.

Journal

Laboratory Investigation cover
Laboratory Investigation
IF:
4.2
Papers:
5.4K
Citations:
1.1W

Organization

C
Chang Gung Memorial Hospital
Scholars:
1.8K
Papers: 708
Citations: 1
I
I-Shou University
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262
Papers: 184
Citations: 2.4K
J
jiann-ren hospital
Scholars:
2
Papers: 1
Citations: 0
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