Transcriptome analysis provides molecular evidence for muscle growth regulation in Litopenaeus vannamei infected with Ecytonucleospora hepatopenaei (EHP)

2026-05-08

PRE

Chuanyu He

Zhipeng Yin

Yajie Tian

杨帆 (Fan Yang)

Zheng Cao

Cuixia Wang

Dongchun Yan

Ting Li

Linrui Chang

Lingjun Si *

DOI：10.1016/j.jip.2026.108648

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• The muscle transcriptome of shrimp infected with EHP was analyzed through RNA-seq. • EHP infection significantly down-regulated the muscle growth-related genes. • EHP infection markedly inhibited the cell division and molting processes. • Humoral immune-related genes ALF and PPAF3 were significantly up-regulated. • EHP infection induces the expression of mTOR pathway and its negative regulators.

Keywords:

muscle growth

EHP infection

transcriptome analysis

mTOR pathway

immune response

Transcriptome analysis provides molecular evidence for muscle growth regulation in Litopenaeus vannamei infected with Ecytonucleospora hepatopenaei (EHP)

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