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Transitions in stress, depression, and self-esteem across pubertal onset in children with central precocious puberty
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DOI：10.1016/j.comppsych.2026.152709.png)
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Abstract
En 中文
• Early-life stress is linked to central precocious puberty (CPP) risk. • Psychological vulnerability precedes puberty onset in children with CPP. • BMI mediates the effect of early-life stress on CPP development. • Findings support early psychosocial and metabolic interventions in childhood.
Keywords:
Central precocious puberty
Pubertal onset
Psychological status
Perceived stress
Depression
Self-esteem
CPP
Central Precocious Puberty
FSH
Follicle-Stimulating Hormone
GLM
Generalized Linear Model
GnRH
Gonadotropin-Releasing Hormone
HPG axis
Hypothalamic–Pituitary–Gonadal axis
LH
Luteinizing Hormone
PSS
Perceived Stress Scale
CES-D
Center for Epidemiologic Studies Depression Scale
RSE
Rosenberg Self-Esteem Scale
zBMI
Age- and sex-specific BMI Z-score
TPLS
Taiwan Pubertal Longitudinal Study
SEM
Structural Equation Modeling
T2
Tanner stage 2
CFI
Comparative fit index
TLI
Tucker-Lewis Index
RMSEA
Root Mean Square Error of Approximation
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