1
Return

Trastuzumab Deruxtecan in Patients From China With Pretreated HER2-Mutant Non-Small Cell Lung Cancer: Final Analysis of the Phase 2, Single-Arm DESTINY-Lung05 Trial

delete2026-06-11
delete0
PRE
AI
Y
Ying Liu *
D
Dairong Li
L
Lin Wu
X
Xingya Li
Y
Yun Fan
M
Mingjun Zhang
J
Jun Guo
Y
Yu Yao
J
Jian Fang
K
Ke-Jing Tang
F
Feng Luo
Y
Yan Yu
X
Xuhong Min
Z
Zizheng Song
J
Jie Hu
R
Rui Ma
H
Huaping Yang
Y
Yongqian Shu
R
Ruilian Xu
B
Buhai Wang
DOI:10.1016/j.cllc.2026.06.003delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
• T-DXd showed antitumor activity in patients from China with pretreated HER2m NSCLC • Confirmed ORR was 56.9%, median PFS was 9.9 months, and median OS was 21.0 months • Confirmed ORRs were consistent across subgroups, including HER2 mutation variants • The safety profile was consistent with the known profile of T-DXd • Results support the use of T-DXd in patients from China with pretreated HER2m NSCLC

Journal

Clinical Lung Cancer cover
Clinical Lung Cancer
IF:
3.3
Papers:
2.4K
Citations:
4.5K

Organization

No organization information available
Cited Papers

Cited Papers

Citing Papers

Citing Papers