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Treatment of Progressive Multifocal Leukoencephalopathy with Third-Party Allogeneic BK Virus T Cells

delete2026-07-06
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OA
AI
A
Amanda Olson
Y
Ye Li
D
David Marin
P
Peter F Thall
R
Roland L Bassett
M
Melissa Barnett
R
Rafet Basar
P
Pinaki P Banerjee
T
T Anne Kleiman
M
Merry Chen
J
Jennie Rexer
J
Jeanie Choi
K
Kim Learned
I
Indreshpal Kaur
M
Melihate Sylejmani
G
Glorette Abueg
R
Roy F Chemaly
V
Victor Mulanovich
R
Rejeena Shrestha
N
Nadima Uprety
K
Karla M Castro
I
Isabel M Galvan
D
Dominique Washington
R
Richard E Champlin
E
Elizabeth J Shpall
K
Katayoun Rezvani
DOI：10.1093/cid/ciag404delete
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Abstract

Abstract

En 中文
Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease caused by JC polyomavirus (JCV) that affects immunosuppressed individuals and has no approved therapy. Here we evaluate the safety and efficacy of third-party, off-the-shelf, partially HLA-matched BK virus-specific T cells (BK-VST) in patients with PML.

Journal

Clinical Infectious Diseases cover
Clinical Infectious Diseases
IF:
7.3
Papers:
2.6W
Citations:
7.8W

Organization

T
The University of Texas MD Anderson Cancer Center
Scholars:
3.3K
Papers: 731
Citations: 5.1W
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