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Type I Interferon Status and Clinical Manifestations in a Large Cohort of Patients with Systemic Lupus Erythematosus
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DOI:10.1016/j.jbspin.2026.106081.png)
Abstract
En 中文
• Elevated interferon gene signature marks higher disease activity and long-term burden in SLE. • IFN-high SLE is associated with greater glucocorticoid and immunosuppressive use. • IFN-high status correlates with broader and more frequent autoantibody positivity. • Interferon gene signature may aid disease stratification and personalized SLE management.
Keywords:
systemic lupus erythematosus
interferon
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