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U-500 regular insulin in automated insulin delivery systems for severe insulin resistance: A single-center retrospective cohort

delete2026-07-26
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PRE
AI
D
David Lee
A
Angela Q. Pham
M
Marconi Abreu *
DOI：10.1016/j.diabres.2026.113460delete
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Abstract

Abstract

En 中文
U-500 regular insulin use in automated insulin delivery systems (AIDs) is off-label and minimally studied. In this four-individual cohort, HbA1c remained stable, time below range stayed low, and no diabetic ketoacidosis or severe hypoglycemia occurred, despite lower TIR. These findings provide early clinical experience to inform cautious, individualized off-label use.

Journal

Diabetes Research and Clinical Practice cover
Diabetes Research and Clinical Practice
IF:
7.4
Papers:
1.1W
Citations:
2.2W

Organization

U
University of Texas Southwestern Medical Center
Scholars:
1.5K
Papers: 720
Citations: 4.4W
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