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Ultra-fast whole-body bone tomoscintigraphies achieved with a high-sensitivity 360° CZT camera and a dedicated deep-learning noise reduction algorithm
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DOI：10.1007/s00259-023-06558-w.png)
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Abstract
En 中文
This study aimed to determine whether the whole-body bone Single Photon Emission Computed Tomography (SPECT) recording times of around 10 min, routinely provided by a high-sensitivity 360 degrees cadmium and zinc telluride (CZT) camera, can be further reduced by a deep-learning noise reduction (DLNR) algorithm. Methods DLNR was applied on whole-body images recorded after the injection of 545 +/- 33 MBq of [99mTc]Tc-HDP in 19 patients (14 with bone metastasis) and reconstructed with 100%, 90%, 80%, 70%, 60%, 50%, 40%, and 30% of the original SPECT recording times. Results Irrespective of recording time, DLNR enhanced the contrast-to-noise ratios and slightly decreased the standardized uptake values of bone lesions. Except in one markedly obese patient, the quality of DLNR processed images remained good-to-excellent down to 60% of the recording time, corresponding to around 6 min SPECT-recording. Conclusion Ultra-fast SPECT recordings of 6 min can be achieved when DLNR is applied on whole-body bone 360 degrees CZT-SPECT.
Keywords:
Bone scintigraphy
Whole-body CZT-camera
Deep learning
Recording time
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