Effect of pusa decomposer-mediated rice residue management on phosphorus fractionation in aggregate size classes under a rice–wheat system

C Mounika

doi:10.1016/j.agee.2025.109994

Ultrasound-Induced Nitric Oxide Release from Isosorbide Dinitrate Nanoparticles for On-Demand Therapy of Periodontitis

2026-08-08

0

PRE

AI

X

Xinchao Wang

Z

Zhilin Liu *

F

Fengli Wu

H

Hang Xu

S

Shujun Dong *

汤

汤朝晖 (Zhaohui Tang)

陈

陈学思 (Xuesi Chen)

DOI：10.1016/j.biomaterials.2026.124535

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• It was revealed that isosorbide dinitrate (ISDN) can be triggered to release nitric oxide under low-intensity ultrasound in the presence of vitamin B2. • Leveraging the property of ISDN, the engineered nanoplatform enables on-demand and spatiotemporally controlled release of nitric oxide. • When combined with ultrasound, the naonoplatform’s antibacterial and anti-biofilm capabilities were enhanced, as evidenced by a bacterial survival rate below 10% with the biofilm during the formation stage. • Superior preservation of alveolar bone and profound elimination of inflammation were achieved with this nanoplatform treatment in the rat periodontal disease model.

Ultrasound-Induced Nitric Oxide Release from Isosorbide Dinitrate Nanoparticles for On-Demand Therapy of Periodontitis

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