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Unmasking NLRX1: Exploring the broadening biological landscape of a mysterious mitochondrial sensor

delete2026-02-10
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PRE
AI
J
Jagabandhu Bag
S
Sabyasachi Banerjee
S
Subhasis Banerjee
S
SK Ashok Kumar
S
Sourav De *
DOI：10.1016/j.mito.2026.102133delete
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Abstract

Abstract

En 中文
• From innate immune signaling to mitochondrial function, NLRX1 serves as linker. • Recognized as a negative regulator of inflammation and immune responses. • It alters metabolism and autophagy across wide variety of disease states. • Represents a promising therapeutic target that remains mechanistically unresolved.
Keywords:
NLRX1
mitochondrial sensor
innate immune signaling
inflammation
autophagy

Journal

MITOCHONDRION cover
MITOCHONDRION
IF:
4.5
Papers:
2.4K
Citations:
5.5K

Organization

N
national cheng kung university
Scholars:
3.0K
Papers: 1.2K
Citations: 0
E
Eminent College of Pharmaceutical Technology
Scholars:
16
Papers: 6
Citations: 0
V
Vellore Institute of Technology
Scholars:
1.3K
Papers: 579
Citations: 8
G
Gupta College of Technological Sciences
Scholars:
9
Papers: 10
Citations: 0
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