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Unveiling Nutraceuticals That Modulate Aging Mechanism: Exploring the Intricate Pathways of Epigenetics
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DOI：10.1002/mnfr.70305.png)
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Abstract
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The world population is aging at an alarming rate, which is an amalgamation of various causative factors. A significant factor contributing to this phenomenon is the dramatic change in the social conditions of the people such as the life style behavioral change, a sedentary pattern of living and a huge dependence on food lacking substantiated nutrition. It has become important to understand the intricate relationship between aging, epigenetics, and nutrition in order to sustain the best possible health and well-being. Aging encompasses numerous molecular, cellular, and systemic changes and is a multifaceted process that involves altered nutrition sensing. Epigenetic factors influence aging. These epigenetic changes affect genes linked to aging and age-related illnesses. A significant obstacle is the identification of key epigenetic markers that can predict health and aging rate. This could help in the prevention of age-related illness and slow the aging process. The precise biochemical mechanisms underlying the interplay between diet and nutrition in epigenetics are still unknown. It is therefore necessary to determine the best food regimens which would lead to epigenetic changes that would help in age gracefully. This research aims to identify a few selected nutrients and their possible effects on epigenetic modulations that might lead to delayed aging.
Keywords:
calorie restriction
DNA methylation
histone modification
one-carbon metabolism
phytochemicals
polyphenols
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