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Usefulness of healthy aging models to study novel prevention strategies in the treatment of cardiac inflammation and atrial fibrillation: A narrative review
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DOI：10.1016/j.arr.2026.103266.png)
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Abstract
En 中文
• Healthy-aging centenarians may be more resistant to age-related cardiac remodeling. • Reduced cardiac oxidative stress may contribute to a lower risk of AF during healthy aging. • The low (<2.5%) prevalence of AF among centenarians may reflect increased resistance to age-related atrial inflammation. • Novel strategies targeting chronic inflammaging and cardiac inflammation may help prevent age-related arrhythmogenesis. • Promotion of healthy lifestyle and appropriate medical therapies may help reduce the risk of AF in older adults.
Keywords:
Healthy Aging
Atrial Fibrillation
Inflammation
Atrial Fibrosis
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