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Versatile Microfluidic Approach to Crystallization

delete2015-04-28
delete19
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OA
AI
张书恒 (Shuheng Zhang)
N
Nathalie Ferte
N
Nadine Candoni
S
Stéphane Veesler *
DOI:10.1021/acs.oprd.5b00122delete
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Abstract

Abstract

En 中文
We present a simple and easy-to-use microfluidic setup for the crystallization of mineral, organic, and biological materials. After briefly presenting the hydrodynamic properties of the setup, we test and validate it with viscous media by crystallizing a protein in an aqueous solution of PEG. We obtain nucleation data in nanocrystallizers using a droplet-based method and precisely controlling input flows to test different crystallization conditions.
Keywords:
PROTEIN CRYSTALLIZATION
DROPLET FORMATION
AQUEOUS-SOLUTIONS
URATE OXIDASE
T-JUNCTION
DEVICE
DYNAMICS
PHYSICS
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

O
Organic Process Research and Development
IF:
3.5
Papers:
5.8K
Citations:
1.1W

Organization

A
aix-marseille universite
Scholars:
3.8W
Papers: 2.7W
Citations: 77