.png){kind=icon}
Return
Versatile Microfluidic Droplets Array for Bioanalysis
.png){kind=icon}
PRE
AI
DOI：10.1021/am5075216.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
We propose a novel method to obtain versatile droplets arrays on a regional hydrophilic chip that is fabricated by PDMS soft lithography and regional plasma treatment. It enables rapid liquid dispensation and droplets array formation just making the chip surface in contact with solution. By combining this chip with a special Christmas Tree structure, the droplets array with concentrations in gradient is generated. It possesses the greatly improved performance of convenience and versatility in bioscreening and biosensing. For example, high throughput condition screening of toxic tests of CdSe quantum dots on HL-60 cells are conducted and cell death rates are successfully counted quickly and efficiently. Furthermore, a rapid biosensing approach for cancer biomarkers carcinoma embryonic antigen (CEA) is developed via magnetic beads (MBs)-based sandwich immunoassay methods.
Keywords:
droplets array
liquid dispensation
rapid analysis
surface wettability
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
8.2
Papers:
6.1W
Citations:
38.7W
Organization
Cited Papers
ShareSaveInfluence of Ag+ Interaction on 1D Droplet Array Spacing and the Repulsive Forces between Stimuli-Responsive Nanoemulsion Droplets.png)
LANGMUIR
LANGMUIRIF3.9
PREAI
ShareSaveNanoporosity-driven superhydrophilicity:: A means to create multifunctional antifogging coatingsLANGMUIR
LANGMUIRIF3.9
PREAI
ShareSaveTrends in miniaturized total analysis systems for point-of-care testing in clinical chemistryLAB ON A CHIP
OAAI
LAB ON A CHIPIF5.4
OAAIShareSaveMicrofluidic device for immunoassays based on surface plasmon resonance imagingLAB ON A CHIP
LAB ON A CHIPIF5.4
PREAI
ShareSaveHigh-performance liquid chromatography (HPLC) determination of inosine, a potential biomarker for initial cardiac ischaemia, using isolated mouse heartsBiomarkers
BiomarkersIF0
PREAI
ShareSaveShareSaveShareSave
View more