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Vertebral endplate bone marrow lesion composition: relation to Modic change classification and associations with chronic low back pain
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DOI：10.1016/j.spinee.2026.05.002.png)
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Abstract
En 中文
Vertebral endplate bone marrow lesions (“Modic changes”, MC) are a putative cause of chronic low back pain in some individuals. However, associations between MC subtypes and clinical symptoms are variable, which limits the utility of conventional imaging in diagnosing and treating chronic low back pain patients with MC.
Keywords:
Chronic low back pain
Modic changes
vertebral endplate bone marrow lesions
vertebral bone marrow composition
biomarkers
water-fat magnetic resonance imaging (MRI)
quantitative magnetic resonance imaging (MRI)
lumbar spine
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