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Vinorelbine and low-dose cyclophosphamide as maintenance therapy in the treatment of Ewing sarcoma rationale for the international INTER-EWING-1 trial for Ewing sarcoma patients
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DOI：10.1016/j.ctrv.2026.103196.png)
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Abstract
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• Maintenance therapy may help prevent relapse in Ewing sarcoma, particularly in multi-metastatic disease. • A literature review provided the rationale for a randomized evaluation of maintenance therapy in the INTER-EWING-1 trial. • Vinorelbine and low-dose cyclophosphamide show a rational and feasible backbone for maintenance therapy in Ewing sarcoma.
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