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Visible-Light-Induced FeCl3-Promoted Dehydroxypropylative Selenylation of Acyclic Alcohols

delete2026-04-01
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PRE
AI
S
Shen, Guo-Min
Z
Zhang, Hong
Y
Yunbing Zhou *
Q
Qiu, Haisheng *
DOI：10.1021/acs.joc.6c00222delete
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Abstract

Abstract

En 中文
A visible-light-induced, FeCl3-promoted dehydroxypropylative selenylation of tertiary acyclic alcohols with diselenides has been developed for constructing unsymmetrical monoselenides. This protocol enables direct C-C bond cleavage and concomitant C-Se bond formation without the need for an additional photocatalyst. The reaction exhibits a broad substrate scope across various diselenides and alcohols and is amenable to gram-scale synthesis. Mechanistic studies support a radical pathway initiated through ligand-to-metal charge transfer (LMCT) upon light irradiation.
Keywords:
CYCLOBUTANOLS REGIOSPECIFIC SYNTHESIS
RING-OPENING FUNCTIONALIZATION
C BOND-CLEAVAGE
CYCLOALKANOLS
ACTIVATION
CYANATION
STRATEGY

Journal

Journal of Organic Chemistry cover
Journal of Organic Chemistry
IF:
3.6
Papers:
5.4W
Citations:
8.8W

Organization

W
wenzhou university
Scholars:
1.7K
Papers: 607
Citations: 1
W
wenzhou medical university
Scholars:
6.2K
Papers: 1.6K
Citations: 0
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