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Visible light-mediated oxidation of benzylic C-H bonds using vitamin B2 as a photocatalyst

delete2026-04-01
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PRE
AI
L
Li, Jinyue
H
Hou, Yujia
M
Ma, Dongzhu
DOI:10.1016/j.tetlet.2026.156068delete
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Abstract

Abstract

En 中文
A visible light-mediated photochemical oxidation of benzylic C-H bonds has been developed using inexpensive and commercially available (-)-riboflavin (vitamin B2) as a photocatalyst. The reaction is conducted in an environmentally benign manner, utilizing air as the oxidant and a mixture of ethanol and water as the solvents, without the need for any additives. This protocol provides a straightforward and mild approach for the direct conversion of alkylbenzenes into ketones.
Keywords:
Photocatalysis
Alkylarenes
Ketones
vitamin B2
Benzylic C-H oxidation

Journal

T
Tetrahedron Letters
IF:
1.5
Papers:
148
Citations:
4.2W

Organization

H
H
Hebei Normal University
Scholars:
6.2K
Papers: 3.4K
Citations: 9
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