1
Return

Yeast Rad55–Rad57–SHU paralog complex dynamically promotes Rad51 filament formation

delete2026-07-21
delete0
PRE
AI
C
Christopher W. Koo
S
Steven K Gore
S
Soo Y. Ro
J
Jie Liu
C
Christine Yu
C
Caleigh M. Azumaya
B
Bobby Brillantes
I
Inna Zilberleyb
H
Henry Chen
M
Mariam B. Rafiqzada
L
Lyra Garcia Sanchez
W
Wolf-Dietrich Heyer
C
Claudio Ciferri *
S
Stanislau Yatskevich *
DOI：10.1016/j.molcel.2026.06.045delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
• Cryo-EM captures six states of the yeast SHU–Rad55–Rad57–Rad51–ssDNA complex • Rad55–Rad57 recruits Rad51 selectively to ssDNA • Rad51 stimulates Rad57 ATP hydrolysis to promote turnover of the paralog complex • SHU couples to Rad55–Rad57 to enhance ssDNA engagement

Journal

Molecular Cell cover
Molecular Cell
IF:
16.6
Papers:
1.0W
Citations:
8.5W

Organization

G
Genentech Inc.
Scholars:
226
Papers: 30
Citations: 0
U
University of California, Davis
Scholars:
274
Papers: 134
Citations: 0
Cited Papers

Cited Papers

Citing Papers

Citing Papers