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Z-DNA Binding Protein 1 Mediates Heat Stress-Induced Neuronal Necroptosis

delete2026-04-30
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OA
AI
J
Jin Deng
Y
Yumeng Gu
Y
Yuchen Li
M
Miaomiao Wei
L
Lin Wang
X
Xin Li *
DOI:10.1016/j.jtherbio.2026.104474delete
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Abstract

Abstract

En 中文
• Heat stress induces brain damage in mice. • HSF1 and ZBP1 are highly expressed in neurons after heat stress. • The ZBP1/RIPK3/MLKL axis mediates heat stress-induced neuronal necroptosis.
Keywords:
ZBP1
HSF1
necroptosis
heat stress
neuronal damage
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Journal of Thermal Biology cover
Journal of Thermal Biology
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tianjin medical university
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