Not logged in QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency Sun, Guohui; Bai, Peiying; Fan, Tengjiao; Zhao, Lijiao; Zhong, Rugang; Mcelhinney, R. Stanley; Mcmurry, T. Brian H.; Donnelly, Dorothy J.; Mccormick, Joan E.; Kelly, Jane; Margison, Geoffrey P. Share Save
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Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries Karniely, S.; Weekes, M. P.; Antrobus, R.; Rorbach, J.; van Haute, L.; Umrania, Y.; Smith, D. L.; Stanton, R. J.; Minczuk, M.; Lehner, P. J.; Sinclair, J. H. Share Save
Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer Drew, Yvette; Ledermann, Jonathan; Hall, Geoff; Rea, Daniel; Glasspool, Ros; Highley, Martin; Jayson, Gordon; Sludden, Julieann; Murray, James; Jamieson, David; Halford, Sarah; Acton, Gary; Backholer, Zoe; Mangano, Raffaella; Boddy, Alan; Curtin, Nicola; Plummer, Ruth Share Save
The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer Wang, Ning; Reeves, Kimberley J.; Brown, Hannah K.; Fowles, Anne C. M.; Docherty, Freyja E.; Ottewell, Penelope D.; Croucher, Peter I.; Holen, Ingunn; Eaton, Colby L. Share Save
Mitotic quiescence, but not unique stemness, marks the phenotype of bone metastasis-initiating cells in prostate cancer Wang, Ning; Docherty, Freyja; Brown, Hannah K.; Reeves, Kim; Fowles, Anne; Lawson, Michelle; Ottewell, Penelope D.; Holen, Ingunn; Croucher, Peter I.; Eaton, Colby L. Share Save
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Decoding the regulatory network of early blood development from single-cell gene expression measurements Moignard, Victoria; Woodhouse, Steven; Haghverdi, Laleh; Lilly, Andrew J.; Tanaka, Yosuke; Wilkinson, Adam C.; Buettner, Florian; Macaulay, Iain C.; Jawaid, Wajid; Diamanti, Evangelia; Nishikawa, Shin-Ichi; Piterman, Nir; Kouskoff, Valerie; Theis, Fabian J.; Fisher, Jasmin; Goettgens, Berthold Share Save
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HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells Autophagy drives compartment-specific oncogenesis Chiavarina, Barbara; Whitaker-Menezes, Diana; Migneco, Gemma; Martinez-Outschoorn, Ubaldo E.; Pavlides, Stephanos; Howell, Anthony; Tanowitz, Herbert B.; Casimiro, Mathew C.; Wang, Chenguang; Pestell, Richard G.; Grieshaber, Philip; Caro, Jaime; Sotgia, Federica; Lisanti, Michael P. Share Save
The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis Bonuccelli, Gloria; Castello-Cros, Remedios; Capozza, Franco; Martinez-Outschoorn, Ubaldo E.; Lin, Zhao; Tsirigos, Aristotelis; Jiao Xuanmao; Whitaker-Menezes, Diana; Howell, Anthony; Lisanti, Michael P.; Sotgia, Federica Share Save
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Vasculogenic mimicry in small cell lung cancer Trapani, F.; Metcalf, R. L.; Polanski, R.; Fusi, A.; Hodgkinson, C.; Nonaka, D.; Hendrix, M. J.; Morrrow, C.; Blackhall, F.; Simpson, K. L.; Dive, C. Share Save
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Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment A new genetically tractable model for human cancer associated fibroblasts Trimmer, Casey; Sotgia, Federica; Whitaker-Menezes, Diana; Balliet, Renee M.; Eaton, Gregory; Martinez-Outschoorn, Ubaldo E.; Pavlides, Stephanos; Howell, Anthony; Iozzo, Renato V.; Pestell, Richard G.; Scherer, Philipp E.; Capozza, Franco; Lisanti, Michael P. Share Save
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Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth Understanding the aging and cancer connection Balliet, Renee M.; Capparelli, Claudia; Guido, Carmela; Pestell, Timothy G.; Martinez-Outschoorn, Ubaldo E.; Lin, Zhao; Whitaker-Menezes, Diana; Chiavarina, Barbara; Pestell, Richard G.; Howell, Anthony; Sotgia, Federica; Lisanti, Michael P. Share Save
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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production Capparelli, Claudia; Guido, Carmela; Whitaker-Menezes, Diana; Bonuccelli, Gloria; Balliet, Renee; Pestell, Timothy G.; Goldberg, Allison F.; Pestell, Richard G.; Howell, Anthony; Sneddon, Sharon; Birbe, Ruth; Tsirigos, Aristotelis; Martinez-Outschoorn, Ubaldo; Sotgia, Federica; Lisanti, Michael P. Share Save