Not logged in PD-L2 blockade elicits IL-17-induced IFNγ to treat melanoma in the aged host through CD8+T and gd T cell effects Tanner, Christopher; Ontiveros, Carlos Oscar; Murray, Clare; Leung, Bernice; Soh, Kah Teong; Krishnan, Shanmugarajan; Chand, Dhan; Turk, Mary Jo; Conejo-Garcia, Jose R.; Curiel, Tyler J. Share Save
Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate Swart, Maarten; Allen, Jessica; Reed, Brendan; Gil, Ana Izquierdo; Verspuij, Johan; Schmit-Tillemans, Sonja; Chakkumkal, Anish; Findeis, Mark; Hafner, Angela V.; Harjivan, Chandresh; Kurnat, Rebecca; Kuipers, Harmjan; Zahn, Roland; Brandenburg, Boerries Share Save
Updated efficacy and safety of botensilimab plus balstilimab in patients with refractory metastatic sarcoma from an expanded phase I study Wilky, B. A.; Trent, J. C.; Tsimberidou, A. M.; Gordon, M.; El-Khoueiry, A. B.; Bullock, A.; Henick, B. S.; Agulnik, M.; Mahadevan, D.; Singh, A.; Wu, W.; Avagyan, M.; Patel, J. M.; Grossman, J.; O'Day, S. J.; Schwartz, G.; Jones, R. L. Share Save
Botensilimab, an Fc-Enhanced Anti-CTLA-4 Antibody, Is Effective against Tumors Poorly Responsive to Conventional Immunotherapy Chand, Dhan; Savitsky, David A.; Krishnan, Shanmugarajan; Mednick, Gabriel; Delepine, Chloe; Garcia-Broncano, Pilar; Soh, Kah Teong; Wu, Wei; Wilkens, Margaret K.; Udartseva, Olga; Vincent, Sylvia; Joshi, Bishnu; Keith, Justin G.; Manrique, Mariana; Marques, Marilyn; Tanne, Antoine; Levey, Daniel L.; Han, Haiyong; Ng, Serina; Ridpath, Jackson; Huber, Olivia; Morin, Benjamin; Galand, Claire; Bourdelais, Sean; Gombos, Randi B.; Ward, Rebecca; Qin, Yu; Waight, Jeremy D.; Costa, Matthew R.; Sebastian-Yague, Alvaro; Rudqvist, Nils-Petter; Pupecka-Swider, Malgorzata; Venkatraman, Vignesh; Slee, Andrew; Patel, Jaymin M.; Grossman, Joseph E.; Wilson, Nicholas S.; Von Hoff, Daniel D.; Stebbing, Justin; Curiel, Tyler J.; Buell, Jennifer S.; O'Day, Steven J.; Stein, Robert B. Share Save
Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: a phase 1 trial Bullock, Andrea J.; Schlechter, Benjamin L.; Fakih, Marwan G.; Tsimberidou, Apostolia M.; Grossman, Joseph E.; Gordon, Michael S.; Wilky, Breelyn A.; Pimentel, Agustin; Mahadevan, Daruka; Balmanoukian, Ani S.; Sanborn, Rachel E.; Schwartz, Gary K.; Abou-Alfa, Ghassan K.; Segal, Neil H.; Bockorny, Bruno; Moser, Justin C.; Sharma, Sunil; Patel, Jaymin M.; Wu, Wei; Chand, Dhan; Rosenthal, Katherine; Mednick, Gabriel; Delepine, Chloe; Curiel, Tyler J.; Stebbing, Justin; Lenz, Heinz-Josef; O'Day, Steven J.; El-Khoueiry, Anthony B. Share Save
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A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome Hammond, Terese C.; Purbhoo, Marco A.; Kadel, Sapana; Ritz, Jerome; Nikiforow, Sarah; Daley, Heather; Shaw, Kit; van Besien, Koen; Gomez-Arteaga, Alexandra; Stevens, Don; Ortuzar, Waldo; Michelet, Xavier; Smith, Rachel; Moskowitz, Darrian; Masakayan, Reed; Yigit, Burcu; Boi, Shannon; Soh, Kah Teong; Chamberland, John; Song, Xin; Qin, Yu; Mishchenko, Ilya; Kirby, Maurice; Nasonenko, Valeriia; Buffa, Alexa; Buell, Jennifer S.; Chand, Dhan; van Dijk, Marc; Stebbing, Justin; Exley, Mark A. Share Save
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Molecular mechanism of phosphopeptide neoantigen immunogenicity Patskovsky, Yury; Natarajan, Aswin; Patskovska, Larysa; Nyovanie, Samantha; Joshi, Bishnu; Morin, Benjamin; Brittsan, Christine; Huber, Olivia; Gordon, Samuel; Michelet, Xavier; Schmitzberger, Florian; Stein, Robert B.; Findeis, Mark A.; Hurwitz, Andy; Van Dijk, Marc; Buell, Jennifer S.; Underwood, Dennis; Krogsgaard, Michelle Share Save
PHASE 1/2 STUDY OF AGENT-797, AN ALLOGENEIC INVARIANT NATURAL KILLER T (INKT) CELL THERAPY, IN SUBJECTS WITH MODERATE TO SEVERE ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) SECONDARY TO SARS-COV-2 (COVID-19) Purbhoo, Marco; Yigit, Burcu; Michelet, Xavier; Smith, Rachel; Moskowitz, Darrian; Kirby, Maurice; Buffa, Alexa; De Munari, Sonia; Feliu, Waldo Ortuzar; Van Besien, Koen; Stevens, Don; Exley, Mark; Hammond, Terese Share Save
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ANTI-PDL2 USES IL17-DRIVEN INTERFERON-GAMMA TO TREAT AGED BUT NOT YOUNG CUTANEOUS MELANOMA-BEARING MICE, AND TREATS OTHER TUMORS IN AN AGE- AND TME-DEPENDENT MANNER Garcia, Myrna; Deng, Yilun; Murray, Clare; Ontiveros, Carlos; Padron, Alvaro; Skopelja-Gardner, Sladjana; Soh, Kah Teong; Chand, Dhan; Curiel, Tyler Share Save
AGENT-797, A NATIVE ALLOGENEIC OFF-THE-SHELF INVARIANT NATURAL KILLER T (INKT) CELL THERAPY PRODUCT IMPROVES EFFECTOR FUNCTIONS WITHIN THE TUMOR MICROENVIRONMENT Pokharel, Sapana; Chamberland, John; Qin, Yu; Moskowitz, Darrian; Masakayan, Reed; Michelet, Xavier; Chand, Dhan; Yigit, Burcu; Van Dijk, Marc Share Save
PHASE I STUDIES OF AGENT-797, A NOVEL ALLOGENEIC INVARIANT NATURAL KILLER T (INKT) CELL THERAPY, FOR THE TREATMENT OF PATIENTS WITH SOLID TUMORS OR MULTIPLE MYELOMA Stevens, Don; Mo, Clifton; Garmezy, Benjamin; Hamm, John; Carneiro, Benedito; Wilky, Breelyn; Sanborn, Rachel; El-Khoueiry, Anthony; Buffa, Alexa; De Munari, Sonia; Yigit, Burcu; Purbhoo, Marco; Exley, Mark; Einstein, David Share Save
PHASE 2 TRIAL OF AGEN1423, AN ANTI-CD73-TGFβ-TRAP BIFUNCTIONAL ANTIBODY, IN COMBINATION WITH BALSTILIMAB, WITH OR WITHOUT CHEMOTHERAPY IN SUBJECTS WITH ADVANCED PANCREATIC CANCER Grossman, Joseph; Patel, Jaymin; Bullock, Bonnie; Morin, Benjamin; Gaynor, Lilian; Hidalgo, Manuel; Bockorny, Bruno Share Save
DEVELOPMENT OF AN ALLOGENIC FAP CAR INKT PRODUCT TO TARGET TUMOR STROMA AND MODULATE THE TUMOR MICROENVIRONMENT Michelet, Xavier; Popis, Martyna; Boi, Shannon; Niedzielska, Magda; Masakayan, Reed; Sharoni, Efrat Altman; Ibbett, Paul; Wright, Deborah; Kalinowska, Barbara Barbara; Keith, Justin; Joshi, Bishnu; Rossi, Moira Pinzan; Smith, Rachel; Yigit, Burcu; Le Tonqueze, Olivier; Chantzoura, Eleni; Van Dijk, Marc Share Save
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