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Transplantation of a genetically modified porcine heart into a live human Griffith, Bartley P.; Grazioli, Alison; Singh, Avneesh K.; Tully, Andy; Galindo, Javier; Saharia, Kapil K.; Shah, Aakash; Strauss, Erik R.; Odonkor, Patrick N.; Williams, Brittney; Silverman, Henry J.; Burke, Allen; Drachenberg, Cinthia B.; Wells, Chris L.; Dickfeld, Timm; Hong, Susie N.; Hicks, Albert J.; Ananthram, Manjula; Gupta, Anuj; Christenson, Robert H.; Tamburro, Lo; Zhang, Tianshu; Hershfeld, Alena; Lewis, Billeta; Feller, Erika D.; Kuravi, Kasinath; Sorrells, Lori; Morgand, Erwan; Mezine, Fariza; Goutaudier, Valentin; Rothblatt, Martine; Lau, Christine L.; Taylor, Bradley; Perrin, Steve; Loupy, Alexandre; Ayares, David; Mohiuddin, Muhammad M. Share Save
Genetically engineered pig heart transplantation in non-human primates Singh, Avneesh K.; Goerlich, Corbin E.; Zhang, Tianshu; Lewis, Billeta; Hershfeld, Alena; Braileanu, Gheorghe; Kurvi, Kasinath; Rice, Kathryn; Sentz, Faith; Mudd, Sarah; Odonkor, Patrick; Strauss, Erik; Williams, Brittney; Burke, Allen; Gupta, Anuj; Drachenberg, Cinthia B.; Ayares, David; Griffith, Bartley P.; Mohiuddin, Muhammad M. Share Save
Ultrasound Assessment of Pleural Effusions After Orthotopic Pig-to-Baboon Cardiac Xenotransplantation Bender, Martin; Radan, Julia; Reichart, Bruno; Leuschen, Maria; Wall, Felicia; Mokelke, Maren; Neumann, Elisabeth; Buttgereit, Ines; Ayares, David; Wolf, Eckhard; Brenner, Paolo; Abicht, Jan-Michael; Laengin, Matthias Share Save
Multi-omic profiling in a human decedent receiving a pig kidney xenograft reveals concerted immune responses preceding a biopsy confirmed rejection event. Keating, Brendan; Khalil, Karen; Kim, Jacqueline; Jaffe, Ian; Lorber, Marc; Ayares, David; Tatapudi, Vasishta; Stern, Jeffrey; Griesemer, Adam; Montgomery, Robert A. Share Save
Can blood products cause antibody-mediated xenograft rejection? Detection and removal of anti-pig xenoantibodies in human blood products. Mangiola, Massimo; Hilbert, Timothy; Dandro, Amy; Fazio-Kroll, Ana; Kim, Jacqueline; Khalil, Karen; Jaffe, Ian; Aljabban, Imad; Stern, Jeffrey M.; Montgomery, Robert A.; Griesemer, Adam Share Save
Combination of Anti-CD40 and Anti-CD40L Antibodies as Co-Stimulation Blockade in Preclinical Cardiac Xenotransplantation Bender, Martin; Abicht, Jan-Michael; Reichart, Bruno; Neumann, Elisabeth; Radan, Julia; Mokelke, Maren; Buttgereit, Ines; Leuschen, Maria; Wall, Felicia; Michel, Sebastian; Ellgass, Reinhard; Steen, Stig; Paskevicius, Audrius; Lange, Andreas; Kessler, Barbara; Kemter, Elisabeth; Klymiuk, Nikolai; Denner, Joachim; Godehardt, Antonia W.; Toenjes, Ralf R.; Burgmann, Jonathan M.; Figueiredo, Constanca; Milusev, Anastasia; Zollet, Valentina; Salimi-Afjani, Neda; Despont, Alain; Rieben, Robert; Ledderose, Stephan; Walz, Christoph; Hagl, Christian; Ayares, David; Wolf, Eckhard; Schmoeckel, Michael; Brenner, Paolo; Binder, Uli; Gebauer, Michaela; Skerra, Arne; Laengin, Matthias Share Save
An Approach to Controlling Inflammation and Coagulation in Pig-to-Baboon Cardiac Xenotransplantation Bender, Martin; Reichart, Bruno; Figueiredo, Constanca; Burgmann, Jonathan M.; Leuschen, Maria; Wall, Felicia; Radan, Julia; Neumann, Elisabeth; Mokelke, Maren; Buttgereit, Ines; Michel, Sebastian; Ellgass, Reinhard; Egerer, Stefanie; Lange, Andreas; Baehr, Andrea; Kessler, Barbara; Kemter, Elisabeth; Klymiuk, Nikolai; Denner, Joachim; Godehardt, Antonia W.; Toenjes, Ralf R.; Hagl, Christian; Gebauer, Michaela; Binder, Uli; Skerra, Arne; Ayares, David; Wolf, Eckhard; Schmoeckel, Michael; Brenner, Paolo; Laengin, Matthias; Abicht, Jan-Michael Share Save
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation Mokelke, Maren; Bender, Martin; Reichart, Bruno; Neumann, Elisabeth; Radan, Julia; Buttgereit, Ines; Ayares, David; Wolf, Eckhard; Brenner, Paolo; Abicht, Jan-Michael; Laengin, Matthias Share Save
Update on the ethical, legal and technical challenges of translating xenotransplantation Thom, Rebecca; Ayares, David; Cooper, David K. C.; Dark, John; Fovargue, Sara; Fox, Marie; Gusmano, Michael; Locke, Jayme; McGregor, Chris; Parent, Brendan; Ravanan, Rommel; Shaw, David; Dorling, Anthony; Cronin, Antonia J. Share Save
Molecular characterization of donor pig of the first human xeno-heart transplant Kuravi, Kasinath; Kokkinaki, Maria; Dandro, Amy; Butler, Stephen; Sorrells, Lori; Rahman, Farzana; Monahan, Jeffrey; Fazio, Ana; Vaught, Todd; Adams, Kent; Ball, Suyapa; Morrill, Benson; Singh, Avneesh; Mohiuddin, Muhammad; Eyestone, Willard; Ayares, David Share Save
Non-thrombogenic costimulation blockade in preclinical cardiac xenotransplantation using a combination of anti-CD40L PAS Fab and chimeric anti-CD40 antibody Abicht, Jan-Michael; Bender, Martin; Reichart, Bruno; Radan, Julia; Neumann, Elisabeth; Buttgereit, Ines; Ayares, David; Wolf, Eckhard; Michel, Sebastian; Binder, Uli; Skerra, Arne; Brenner, Paolo; Laengin, Matthias Share Save
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Integrative omic profiling and analyses in two pig heart to human xenotransplants Keating, Brendan; Schmauch, Eloi; Piening, Brian; Xia, Bo; Zhu, Chenchen; Chang, Boa-Li; Khalil, Karen; Kim, Jacqueline; Weldon, Elaina; Pass, Harvey; Ayares, David; Griesemer, Adam; Mangiola, Massimo; Stern, Jeffrey; Snyder, Michael P.; Boeke, Jef; Montgomery, Robert A. Share Save
Recovery from perioperative cardiac xenograft dysfunction and consequences of cardiac overgrowth in pig-to-baboon heterotopic thoracic cardiac xenotransplantation Bender, Martin; Reichart, Bruno; Radan, Julia; Neumann, Elisabeth; Buttgereit, Ines; Ayares, David; Wolf, Eckhard; Brenner, Paolo; Laengin, Matthias; Abicht, Jan-Michael Share Save
Immunotranscriptomic changes during two pig-to-human kidney xenotransplantation cases Pass, Harvey; Goparaju, Chandra; Stern, Jeffrey; Khalil, Karen; Kim, Jacqueline; Lonze, Bonnie; Stewart, Zoe A.; Griesemer, Adam; Weldon, Elaina; Ayares, David; Keating, Brendan; Montgomery, Robert A. Share Save
Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study Loupy, Alexandre; Goutaudier, Valentin; Giarraputo, Alessia; Mezine, Fariza; Morgand, Erwan; Robin, Blaise; Khalil, Karen; Mehta, Sapna; Keating, Brendan; Dandro, Amy; Certain, Anais; Tharaux, Pierre-Louis; Narula, Navneet; Tissier, Renaud; Giraud, Sebastien; Hauet, Thierry; Pass, Harvey, I; Sannier, Aurelie; Wu, Ming; Griesemer, Adam; Ayares, David; Tatapudi, Vasishta; Stern, Jeffrey; Lefaucheur, Carmen; Bruneval, Patrick; Mangiola, Massimo; Montgomery, Robert A. Share Save
Renin-angiotensin-aldosterone system function in the pig-to-baboon kidney xenotransplantation model Hansen-Estruch, Christophe; Bikhet, Mohamed H.; Javed, Mariyam; Katsurada, Akemi; Satou, Ryousuke; Shao, Weijian; Ayares, David; Venkataramanan, Raman; Cooper, David K. C.; Judd, Eric; Navar, Luis Gabriel Share Save
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation Montgomery, Robert A.; Stern, Jeffrey M.; Lonze, Bonnie E.; Tatapudi, Vasishta S.; Mangiola, Massimo; Wu, Ming; Weldon, Elaina; Lawson, Nikki; Deterville, Cecilia; Dieter, Rebecca A.; Sullivan, Brigitte; Boulton, Gabriella; Parent, Brendan; Piper, Greta; Sommer, Philip; Cawthon, Samantha; Duggan, Erin; Ayares, David; Dandro, Amy; Fazio-Kroll, Ana; Kokkinaki, Maria; Burdorf, Lars; Lorber, Marc; Boeke, Jef D.; Pass, Harvey; Keating, Brendan; Griesemer, Adam; Ali, Nicole M.; Mehta, Sapna A.; Stewart, Zoe A. Share Save
Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons Iwase, Hayato; Jagdale, Abhijit; Yamamoto, Takayuki; Bikhet, Mohamed H.; Nguyen, Huy Q.; Ezzelarab, Mohamed; Ayares, David; Anderson, Douglas J.; Eckhoff, Devin E.; Foote, Jeremy B.; Fatima, Huma; Schuurman, Hendrik Jan; Hara, Hidetaka; Cooper, David K. C. Share Save
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