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Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network Lee, Richard G.; Rudler, Danielle L.; Raven, Samuel A.; Peng, Liuyu; Chopin, Anaelle; Moh, Edward S. X.; Mccubbin, Tim; Siira, Stefan J.; Fagan, Samuel V.; Debono, Nicholas J.; Stentenbach, Maike; Browne, Jasmin; Rackham, Filip F.; Li, Ji; Simpson, Kaylene J.; Marcellin, Esteban; Packer, Nicolle H.; Reid, Gavin E.; Padman, Benjamin S.; Rackham, Oliver; Filipovska, Aleksandra Share Save
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ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription Dai, Chuan-Yang; Ng, Chai Chee; Hung, Grace Ching Ching; Kirmes, Ina; Hughes, Laetitia A. A.; Du, Yunguang; Brosnan, Christopher A. A.; Ahier, Arnaud; Hahn, Anne; Haynes, Cole M. M.; Rackham, Oliver; Filipovska, Aleksandra; Zuryn, Steven Share Save
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer Stentenbach, Maike; Ermer, Judith A.; Rudler, Danielle L.; Perks, Kara L.; Raven, Samuel A.; Lee, Richard G.; McCubbin, Tim; Marcellin, Esteban; Siira, Stefan J.; Rackham, Oliver; Filipovska, Aleksandra Share Save
Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation Hughes, Laetitia A.; Rudler, Danielle L.; Siira, Stefan J.; McCubbin, Tim; Raven, Samuel A.; Browne, Jasmin M.; Ermer, Judith A.; Rientjes, Jeanette; Rodger, Jennifer; Marcellin, Esteban; Rackham, Oliver; Filipovska, Aleksandra Share Save
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ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing Clemente, Paula; Calvo-Garrido, Javier; Pearce, Sarah F.; Schober, Florian A.; Shigematsu, Megumi; Siira, Stefan J.; Laine, Isabelle; Spahr, Henrik; Steinmetzger, Christian; Petzold, Katja; Kirino, Yohei; Wibom, Rolf; Rackham, Oliver; Filipovska, Aleksandra; Rorbach, Joanna; Freyer, Christoph; Wredenberg, Anna Share Save
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Computationally designed hyperactive Cas9 enzymes Vos, Pascal D.; Rossetti, Giulia; Mantegna, Jessica L.; Siira, Stefan J.; Gandadireja, Andrianto P.; Bruce, Mitchell; Raven, Samuel A.; Khersonsky, Olga; Fleishman, Sarel J.; Filipovska, Aleksandra; Rackham, Oliver Share Save
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Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease Lee, Richard G.; Balasubramaniam, Shanti; Stentenbach, Maike; Kralj, Tom; McCubbin, Timothy; Padman, Benjamin; Smith, Janine; Riley, Lisa G.; Priyadarshi, Archana; Peng, Liuyu; Nuske, Madison R.; Webster, Richard; Peacock, Ken; Roberts, Philip; Stark, Zornitza; Lemire, Gabrielle; Ito, Yoko A.; Boycott, Kym M.; Geraghty, Michael T.; Klinken, Jan Bert; Ferdinandusse, Sacha; Zhou, Ying; Walsh, Rebecca; Marcellin, Esteban; Thorburn, David R.; Rosciolli, Tony; Fletcher, Janice; Rackham, Oliver; Vaz, Frederic M.; Reid, Gavin E.; Filipovska, Aleksandra Share Save
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A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance Rossetti, Giulia; Ermer, Judith A.; Stentenbach, Maike; Siira, Stefan J.; Richman, Tara R.; Milenkovic, Dusanka; Perks, Kara L.; Hughes, Laetitia A.; Jamieson, Emma; Xiafukaiti, Gulibaikelamu; Ward, Natalie C.; Takahashi, Satoru; Gray, Nicola; Viola, Helena M.; Hool, Livia C.; Rackham, Oliver; Filipovska, Aleksandra Share Save
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