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Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany Russ, Anne-Kathrin; Schreiber, Stefan; Lieb, Wolfgang; Vehreschild, J. Janne; Heuschmann, Peter U.; Illig, Thomas; Appel, Katharina S.; Vehreschild, Maria J. G. T.; Krefting, Dagmar; Reinke, Lennart; Viebke, Alin; Poick, Susanne; Stoerk, Stefan; Reese, Jens-Peter; Zoller, Thomas; Krist, Lilian; Ellinghaus, David; Foesel, Baerbel U.; Gieger, Christian; Lorenz-Depiereux, Bettina; Witzenrath, Martin; Anton, Gabriele; Krawczak, Michael; Heyckendorf, Jan; Bahmer, Thomas Share Save
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Machine learning approach on plasma proteomics identifies signatures associated with obesity in the KORA FF4 cohort Niu, Jiefei; Adam, Jonathan; Skurk, Thomas; Seissler, Jochen; Dong, Qiuling; Efiong, Esienanwan; Gieger, Christian; Peters, Annette; Sharma, Sapna; Grallert, Harald Share Save
Interpretable multimodal machine learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy Nguyen, Phong B. H.; Garger, Daniel; Lu, Diyuan; Maalmi, Haifa; Prokisch, Holger; Thorand, Barbara; Adamski, Jerzy; Kastenmueller, Gabi; Waldenberger, Melanie; Gieger, Christian; Peters, Annette; Suhre, Karsten; Boenhof, Gidon J.; Rathmann, Wolfgang; Roden, Michael; Grallert, Harald; Ziegler, Dan; Herder, Christian; Menden, Michael P. Share Save
RESULTS FROM THE LARGEST META-GWAS PERFORMED ON PCSK9 CONCENTRATIONS Kheirkhah, Azin; Schachtl-Riess, Johanna F.; Lamina, Claudia; Di Maio, Silvia; Koller, Adriana; Schoenherr, Sebastian; Coassin, Stefan; Forer, Lukas; Sekula, Peggy; Gieger, Christian; Peters, Annette; Koettgen, Anna; Eckardt, Kai-Uwe; Kronenberg, Florian Share Save
Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline Wiegrebe, Simon; Gorski, Mathias; Herold, Janina M.; Stark, Klaus J.; Thorand, Barbara; Gieger, Christian; Boeger, Carsten A.; Schoedel, Johannes; Hartig, Florian; Chen, Han; Winkler, Thomas W.; Kuechenhoff, Helmut; Heid, Iris M. Share Save
Association analysis between an epigenetic alcohol risk score and blood pressure Bui, Helena; Keshawarz, Amena; Wang, Mengyao; Lee, Mikyeong; Ratliff, Scott M.; Lin, Lisha; Birditt, Kira S.; Faul, Jessica D.; Peters, Annette; Gieger, Christian; Delerue, Thomas; Kardia, Sharon L. R.; Zhao, Wei; Guo, Xiuqing; Yao, Jie; Rotter, Jerome I.; Li, Yi; Liu, Xue; Liu, Dan; Tavares, Juliana F.; Pehlivan, Goekhan; Breteler, Monique M. B.; Karabegovic, Irma; Ochoa-Rosales, Carolina; Voortman, Trudy; Ghanbari, Mohsen; van Meurs, Joyce B. J.; Nasr, Mohamed Kamal; Doerr, Marcus; Grabe, Hans J.; London, Stephanie J.; Teumer, Alexander; Waldenberger, Melanie; Weir, David R.; Smith, Jennifer A.; Levy, Daniel; Ma, Jiantao; Liu, Chunyu Share Save
Subphenotypes of adult-onset diabetes: Data-driven clustering in the population-based KORA cohort Dong, Qiuling; Xi, Yue; Brandmaier, Stefan; Fuchs, Marketa; Huemer, Marie-Theres; Waldenberger, Melanie; Niu, Jiefei; Herder, Christian; Rathmann, Wolfgang; Roden, Michael; Koenig, Wolfgang; Boenhof, Gidon J.; Gieger, Christian; Thorand, Barbara; Peters, Annette; Rospleszcz, Susanne; Grallert, Harald Share Save
Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity Carper, Deborah; Lac, Marlene; Coue, Marine; Labour, Axel; Maertens, Andre; Banda, Jorge Alberto Ayala; Mazeyrie, Laurene; Mechta, Mie; Ingerslev, Lars Roed; Elhadad, Mohamed; Petit, Justine Vily; Maslo, Claire; Monbrun, Laurent; Del Carmine, Peggy; Sainte-Marie, Yannis; Bourlier, Virginie; Laurens, Claire; Mithieux, Gilles; Joanisse, Denis R.; Coudray, Charles; Feillet-Coudray, Christine; Montastier, Emilie; Viguerie, Nathalie; Tavernier, Genevieve; Waldenberger, Melanie; Peters, Annette; Wang-Sattler, Rui; Adamski, Jerzy; Suhre, Karsten; Gieger, Christian; Kastenmueller, Gabi; Illig, Thomas; Lichtinghagen, Ralf; Seissler, Jochen; Mounier, Remy; Hiller, Karsten; Jordan, Jens; Barres, Romain; Kuhn, Michaela; Pesta, Dominik; Moro, Cedric Share Save
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Understanding the genetic complexity of puberty timing across the allele frequency spectrum Kentistou, Katherine A.; Kaisinger, Lena R.; Stankovic, Stasa; Vaudel, Marc; de Oliveira, Edson Mendes; Messina, Andrea; Walters, Robin G.; Liu, Xiaoxi; Busch, Alexander S.; Helgason, Hannes; Thompson, Deborah J.; Santoni, Federico; Petricek, Konstantin M.; Zouaghi, Yassine; Huang-Doran, Isabel; Gudbjartsson, Daniel F.; Bratland, Eirik; Lin, Kuang; Gardner, Eugene J.; Zhao, Yajie; Jia, Raina Y.; Terao, Chikashi; Riggan, Marjorie J.; Bolla, Manjeet K.; Yazdanpanah, Mojgan; Yazdanpanah, Nahid; Bradfield, Jonathan P.; Broer, Linda; Campbell, Archie; Chasman, Daniel I.; Cousminer, Diana L.; Franceschini, Nora; Franke, Lude H.; Girotto, Giorgia; He, Chunyan; Jarvelin, Marjo-Riitta; Joshi, Peter K.; Kamatani, Yoichiro; Karlsson, Robert; Luan, Jian'an; Lunetta, Kathryn L.; Magi, Reedik; Mangino, Massimo; Medland, Sarah E.; Meisinger, Christa; Noordam, Raymond; Nutile, Teresa; Concas, Maria Pina; Polasek, Ozren; Porcu, Eleonora; Ring, Susan M.; Sala, Cinzia; Smith, Albert V.; Tanaka, Toshiko; Van der Most, Peter J.; Vitart, Veronique; Wang, Carol A.; Willemsen, Gonneke; Zygmunt, Marek; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Auer, Paul L.; Barnes, Catriona L. K.; Beckmann, Matthias W.; de Gonzalez, Amy Berrington; Bogdanova, Natalia V.; Bojesen, Stig E.; Brenner, Hermann; Buring, Julie E.; Canzian, Federico; Chang-Claude, Jenny; Couch, Fergus J.; Cox, Angela; Crisponi, Laura; Czene, Kamila; Daly, Mary B.; Demerath, Ellen W.; Dennis, Joe; Devilee, Peter; De Vivo, Immaculata; Doerk, Thilo; Dunning, Alison M.; Dwek, Miriam; Eriksson, Johan G.; Fasching, Peter A.; Fernandez-Rhodes, Lindsay; Ferreli, Liana; Fletcher, Olivia; Gago-Dominguez, Manuela; Garcia-Closas, Montserrat; Garcia-Saenz, Jose A.; Gonzalez-Neira, Anna; Grallert, Harald; Guenel, Pascal; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Hakonarson, Hakon; Hart, Roger J.; Hickey, Martha; Hooning, Maartje J.; Hoppe, Reiner; Hopper, John L.; Hottenga, Jouke-Jan; Hu, Frank B.; Huebner, Hanna; Hunter, David J.; Jernstrom, Helena; John, Esther M.; Karasik, David; Khusnutdinova, Elza K.; Kristensen, Vessela N.; Lacey, James V.; Lambrechts, Diether; Launer, Lenore J.; Lind, Penelope A.; Lindblom, Annika; Magnusson, Patrik K. E.; Mannermaa, Arto; McCarthy, Mark I.; Meitinger, Thomas; Menni, Cristina; Michailidou, Kyriaki; Millwood, Iona Y.; Milne, Roger L.; Montgomery, Grant W.; Nevanlinna, Heli; Nolte, Ilja M.; Nyholt, Dale R.; Obi, Nadia; O'Brien, Katie M.; Offit, Kenneth; Oldehinkel, Albertine J.; Ostrowski, Sisse R.; Palotie, Aarno; Pedersen, Ole B.; Peters, Annette; Pianigiani, Giulia; Plaseska-Karanfilska, Dijana; Pouta, Anneli; Pozarickij, Alfred; Radice, Paolo; Rennert, Gad; Rosendaal, Frits R.; Ruggiero, Daniela; Saloustros, Emmanouil; Sandler, Dale P.; Schipf, Sabine; Schmidt, Carsten O.; Schmidt, Marjanka K.; Small, Kerrin; Spedicati, Beatrice; Stampfer, Meir; Stone, Jennifer; Tamimi, Rulla M.; Teras, Lauren R.; Tikkanen, Emmi; Turman, Constance; Vachon, Celine M.; Wang, Qin; Winqvist, Robert; Wolk, Alicja; Zemel, Babette S.; Zheng, Wei; van Dijk, Ko W.; Alizadeh, Behrooz Z.; Bandinelli, Stefania; Boerwinkle, Eric; Boomsma, Dorret I.; Ciullo, Marina; Chenevix-Trench, Georgia; Cucca, Francesco; Esko, Tonu; Gieger, Christian; Grant, Struan F. A.; Gudnason, Vilmundur; Hayward, Caroline; Kolcic, Ivana; Kraft, Peter; Lawlor, Deborah A.; Martin, Nicholas G.; Nohr, Ellen A.; Pedersen, Nancy L.; Pennell, Craig E.; Ridker, Paul M.; Robino, Antonietta; Snieder, Harold; Sovio, Ulla; Spector, Tim D.; Stockl, Doris; Sudlow, Cathie; Timpson, Nic J.; Toniolo, Daniela; Uitterlinden, Andre; Ulivi, Sheila; Volzke, Henry; Wareham, Nicholas J.; Widen, Elisabeth; Wilson, James F.; Pharoah, Paul D. P.; Li, Liming; Easton, Douglas F.; Njolstad, Pal R.; Sulem, Patrick; Murabito, Joanne M.; Murray, Anna; Manousaki, Despoina; Juul, Anders; Erikstrup, Christian; Stefansson, Kari; Horikoshi, Momoko; Chen, Zhengming; Farooqi, I. Sadaf; Pitteloud, Nelly; Johansson, Stefan; Day, Felix R.; Perry, John R. B.; Ong, Ken K. Share Save
Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i Harada, Makoto; Adam, Jonathan; Covic, Marcela; Ge, Jianhong; Brandmaier, Stefan; Muschet, Caroline; Huang, Jialing; Han, Siyu; Rommel, Martina; Rotter, Markus; Heier, Margit; Mohney, Robert P.; Krumsiek, Jan; Kastenmueller, Gabi; Rathmann, Wolfgang; Zou, Zhongmei; Zukunft, Sven; Scheerer, Markus F.; Neschen, Susanne; Adamski, Jerzy; Gieger, Christian; Peters, Annette; Ankerst, Donna P.; Meitinger, Thomas; Alderete, Tanya L.; de Angelis, Martin Hrabe; Suhre, Karsten; Wang-Sattler, Rui Share Save
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction Schormair, Barbara; Zhao, Chen; Bell, Steven; Didriksen, Maria; Nawaz, Muhammad S.; Schandra, Nathalie; Stefani, Ambra; Hoegl, Birgit; Dauvilliers, Yves; Bachmann, Cornelius G.; Kemlink, David; Sonka, Karel; Paulus, Walter; Trenkwalder, Claudia; Oertel, Wolfgang H.; Hornyak, Magdolna; Teder-Laving, Maris; Metspalu, Andres; Hadjigeorgiou, Georgios M.; Polo, Olli; Fietze, Ingo; Ross, Owen A.; Wszolek, Zbigniew K.; Ibrahim, Abubaker; Bergmann, Melanie; Kittke, Volker; Harrer, Philip; Dowsett, Joseph; Chenini, Sofiene; Ostrowski, Sisse Rye; Sorensen, Erik; Erikstrup, Christian; Pedersen, Ole B.; Bruun, Mie Topholm; Nielsen, Kaspar R.; Butterworth, Adam S.; Soranzo, Nicole; Ouwehand, Willem H.; Roberts, David J.; Danesh, John; Burchell, Brendan; Furlotte, Nicholas A.; Nandakumar, Priyanka; Earley, Christopher J.; Ondo, William G.; Xiong, Lan; Desautels, Alex; Perola, Markus; Vodicka, Pavel; Dina, Christian; Stoll, Monika; Franke, Andre; Lieb, Wolfgang; Stewart, Alexandre F. R.; Shah, Svati H.; Gieger, Christian; Peters, Annette; Rye, David B.; Rouleau, Guy A.; Berger, Klaus; Stefansson, Hreinn; Ullum, Henrik; Stefansson, Kari; Hinds, David A.; Di Angelantonio, Emanuele; Oexle, Konrad; Winkelmann, Juliane Share Save
Plasma proteome association with coronary heart disease and carotid intima media thickness: results from the KORA F4 study Elhadad, Mohamed A.; del C. Gomez-Alonso, Monica; Chen, Chien-Wei; Neumeyer, Sonja; Delerue, Thomas; Rathmann, Wolfgang; Naebauer, Michael; Meisinger, Christa; Kaeaeb, Stefan; Seissler, Jochen; Graumann, Johannes; Koenig, Wolfgang; Suhre, Karsten; Gieger, Christian; Voelker, Uwe; Peters, Annette; Hammer, Elke; Waldenberger, Melanie Share Save
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits Keaton, Jacob M.; Kamali, Zoha; Xie, Tian; Vaez, Ahmad; Williams, Ariel; Goleva, Slavina B.; Ani, Alireza; Evangelou, Evangelos; Hellwege, Jacklyn N.; Yengo, Loic; Young, William J.; Traylor, Matthew; Giri, Ayush; Zheng, Zhili; Zeng, Jian; Chasman, Daniel I.; Morris, Andrew P.; Caulfield, Mark J.; Hwang, Shih-Jen; Kooner, Jaspal S.; Conen, David; Attia, John R.; Morrison, Alanna C.; Loos, Ruth J. F.; Kristiansson, Kati; Schmidt, Reinhold; Hicks, Andrew A.; Pramstaller, Peter P.; Nelson, Christopher P.; Samani, Nilesh J.; Risch, Lorenz; Gyllensten, Ulf; Melander, Olle; Riese, Harriette; Wilson, James F.; Campbell, Harry; Rich, Stephen S.; Psaty, Bruce M.; Lu, Yingchang; Rotter, Jerome I.; Guo, Xiuqing; Rice, Kenneth M.; Vollenweider, Peter; Sundstrom, Johan; Langenberg, Claudia; Tobin, Martin D.; Giedraitis, Vilmantas; Luan, Jian'an; Tuomilehto, Jaakko; Kutalik, Zoltan; Ripatti, Samuli; Salomaa, Veikko; Girotto, Giorgia; Trompet, Stella; Jukema, J. Wouter; van der Harst, Pim; Ridker, Paul M.; Giulianini, Franco; Vitart, Veronique; Goel, Anuj; Watkins, Hugh; Harris, Sarah E.; Deary, Ian J.; van der Most, Peter J.; Oldehinkel, Albertine J.; Keavney, Bernard D.; Hayward, Caroline; Campbell, Archie; Boehnke, Michael; Scott, Laura J.; Boutin, Thibaud; Mamasoula, Chrysovalanto; Jarvelin, Marjo-Riitta; Peters, Annette; Gieger, Christian; Lakatta, Edward G.; Cucca, Francesco; Hui, Jennie; Knekt, Paul; Enroth, Stefan; De Borst, Martin H.; Polasek, Ozren; Concas, Maria Pina; Catamo, Eulalia; Cocca, Massimiliano; Li-Gao, Ruifang; Hofer, Edith; Schmidt, Helena; Spedicati, Beatrice; Waldenberger, Melanie; Strachan, David P.; Laan, Maris; Teumer, Alexander; Dorr, Marcus; Gudnason, Vilmundur; Cook, James P.; Ruggiero, Daniela; Kolcic, Ivana; Boerwinkle, Eric; Traglia, Michela; Lehtimaki, Terho; Raitakari, Olli T.; Johnson, Andrew D.; Newton-Cheh, Christopher; Brown, Morris J.; Dominiczak, Anna F.; Sever, Peter J.; Poulter, Neil; Chambers, John C.; Elosua, Roberto; Siscovick, David; Esko, Tonu; Metspalu, Andres; Strawbridge, Rona J.; Laakso, Markku; Hamsten, Anders; Hottenga, Jouke-Jan; de Geus, Eco; Morris, Andrew D.; Palmer, Colin N. A.; Nolte, Ilja M.; Milaneschi, Yuri; Marten, Jonathan; Wright, Alan; Zeggini, Eleftheria; Howson, Joanna M. M.; O'Donnell, Christopher J.; Spector, Tim; Nalls, Mike A.; Simonsick, Eleanor M.; Liu, Yongmei; van Duijn, Cornelia M.; Butterworth, Adam S.; Danesh, John N.; Menni, Cristina; Wareham, Nicholas J.; Khaw, Kay-Tee; Sun, Yan V.; Wilson, Peter W. F.; Cho, Kelly; Visscher, Peter M.; Denny, Joshua C.; Levy, Daniel; Edwards, Todd L.; Munroe, Patricia B.; Snieder, Harold; Warren, Helen R. Share Save
Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function Yu, Shixiang; Han, Siyu; Shi, Mengya; Harada, Makoto; Ge, Jianhong; Li, Xuening; Cai, Xiang; Heier, Margit; Karstenmueller, Gabi; Suhre, Karsten; Gieger, Christian; Koenig, Wolfgang; Rathmann, Wolfgang; Peters, Annette; Wang-Sattler, Rui Share Save
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019) Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B.; Zhou, Jian; Hui, Jennie; Karrasch, Stefan; Imboden, Medea; Harris, Sarah E.; Marten, Jonathan; Enroth, Stefan; Kerr, Shona M.; Surakka, Ida; Vitart, Veronique; Lehtimaeki, Terho; Allen, Richard J.; Bakke, Per S.; Beaty, Terri H.; Bleecker, Eugene R.; Bosse, Yohan; Brandsma, Corry-Anke; Chen, Zhengming; Crapo, James D.; Danesh, John; DeMeo, Dawn L.; Dudbridge, Frank; Ewert, Ralf; Gieger, Christian; Gulsvik, Amund; Hansell, Anna L.; Hao, Ke; Hoffman, Joshua D.; Hokanson, John E.; Homuth, Georg; Joshi, Peter K.; Joubert, Philippe; Langenberg, Claudia; Li, Xuan; Li, Liming; Lin, Kuang; Lind, Lars; Locantore, Nicholas; Luan, Jian'an; Mahajan, Anubha; Maranville, Joseph C.; Murray, Alison; Nickle, David C.; Packer, Richard; Parker, Margaret M.; Paynton, Megan L.; Porteous, David J.; Prokopenko, Dmitry; Qiao, Dandi; Rawal, Rajesh; Runz, Heiko; Sayers, Ian; Sin, Don D.; Smith, Blair H.; Artigas, Maria Soler; Sparrow, David; Tal-Singer, Ruth; Timmers, Paul R. H. J.; Van den Berge, Maarten; Whittaker, John C.; Woodruff, Prescott G.; Yerges-Armstrong, Laura M.; Troyanskaya, Olga G.; Raitakari, Olli T.; Kaehoenen, Mika; Polasek, Ozren; Gyllensten, Ulf; Rudan, Igor; Deary, Ian J.; Probst-Hensch, Nicole M.; Schulz, Holger; James, Alan L.; Wilson, James F.; Stubbe, Beate; Zeggini, Eleftheria; Jarvelin, Marjo-Riitta; Wareham, Nick; Silverman, Edwin K.; Hayward, Caroline; Morris, Andrew P.; Butterworth, Adam S.; Scott, Robert A.; Walters, Robin G.; Meyers, Deborah A.; Cho, Michael H.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D.; Wain, Louise V. Share Save
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