刘文涛｜Wentao Liu

nanjing medical university教授

H-index:33

Citation Count:2,702

Biography

"刘文涛作者：基础医学院日期：2015-11-30 点击：26457 刘文涛教授，理学博士，博士生导师科学研究方向慢性疼痛的发病机制与药物治疗联系方式通讯：江苏省南京市江宁区龙眠大道101号学海楼，邮编211166电话：025-86869407电邮：wtliu@njmu.edu.cn简介现为南京医科大学基础医学院药理学系教授。主要研究方向为慢性疼痛的发病机制与药物治疗。过去几年在The Journal of Neuroscience、Cancer Research、FASEB Journal、Pain、Anesthesiology，Journal of Neuroinflammation等SCI杂志上以第一作者和通讯作者身份，发表20多篇SCI文章。现任中国药理学会麻醉药理专业委员常委，中国药理学会肾脏药理专业委员会常委，中国研究型医院麻醉专业委员会委员，江苏省神经免疫学会副主任委员，江苏省医学会疼痛医学委员会委员。承担国家自然科学基金多项。学术兼职现任中国药理学会麻醉药理专业委员常委，中国药理学会肾脏药理专业委员会常委，中国研究型医院麻醉专业委员会委员，江苏省神经免疫学会副主任委员，江苏省医学会疼痛医学委员会委员，南京医学会疼痛医学委员会委员承担科研课题1. 国家自然科学基金面上项目，81471142，选择性调控AMPKα1及α2不同亚型实现能量再平衡治疗神经病理性疼痛，2014/1-2018/12，70万，在研2. 国家自然科学基金面上项目，81171697，K-ATP通道调控神经病理性疼痛-DRG与脊髓机制研究，2011/1-2015/12，58万，已结题3. 国家自然科学基金青年科学基金项目，30901401，EphrinB-EphB 信号系统调控吗啡成瘾及耐受-脊髓与初级感觉神经元机制研究，2009/1-2012/12，32万，已结题近五年代表性论文、专利1. Yi-Xin Fan, Cheng Qian,Bingqian Liu, Chaoyu Wang, Haijiao Liu, XiuxiuPan, PengTeng Liang Hu, Guangqin Zhang, Yuan-Han, Mi Yang, Xue-Feng Wu and Wen-Tao Liu *. Induction of suppressor of cytokine signaling 3 via HSF-1-HSP70-TLR4 axis attenuates neuroinflammation and ameliorates postoperative pain. Brain, Behavior, and Immunity. 2018 Feb;68:111-122. doi: 10.1016 (IF=6.3)2. Yan Zhang†, Gao-Jian Tao†, Liang Hu, Jie Qu, Yuan Han, Guangqin Zhang, Yanning Qian, Chun-Yi Jiang* and Wen-Tao Liu*. Lidocaine alleviates morphine tolerance via AMPK-SOCS3-dependent neuroinflammation suppression in the spinal cord. Journal of Neuroinflammation, 2017. 201714:211 10.1186/s12974-017-0983-6 (IF=5.1)3. Jie Qu , Xue-You Tao , Peng Teng , Yan Zhang, Ci-Liang Guo , Liang Hu , Yan-Ning Qian , Chun-Yi Jiang* and Wen-Tao Liu*. Blocking ATP-sensitive potassium channel alleviates morphine tolerance by inhibiting HSP70-TLR4-NLRP3-mediated neuroinflammation. Journal of Neuroinflammation, 2017. DOI : 10.1186/s12974-017-0997-0 (IF=5.1)4. Lai Jiang,# Cai-Long Pan,# Chao-Yu Wang, Bing-Qian Liu, Yuan Han, Liang Hu, Lei Liu, Yang Yang, Jun-Wei Qu and Wen-Tao Liu *. Selective suppression of the JNK-MMP2/9 signal pathway by tetramethylpyrazine attenuates neuropathic pain in rats. Journal of Neuroinflammation, 2017. 14:74 2017 Aug 31. doi: 10.1186/s12974-017-0947-x (IF=5.1)5. Xiang yuYang, Guiqin He,Xiaoyun Zhang,Lu Chen,Yue Kong, Wei Xie, Zhengping Jia, Wen-Tao Liu *and Zikai Zhou* Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain. Neuropharmacology. 2017 Oct;125:284-294. doi: 10.1016(IF=5.1)6. Hai-Jiao Liu†, Xiu-Xiu Pan†, Bing-Qian Liu, Xuan Gui, Liang Hu, Chun-Yi Jiang, Yuan Han, Yi-Xin Fan, Yu-Lin Tang and Wen-Tao Liu*. Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression. Journal of Neuroinflammation, 2017. 14:74 DOI: 10.1186 (IF=5.1)7. Hong ZW, Tian YJ, Qi MW, Li YC, Du TM, Chen L*, Liu WT*, Chen L, Transient Receptor Potential Vanilloid 4 Inhibits γ-Aminobutyric Acid-Activated Current in Hippocampal Pyramidal Neurons, Front Molecular Neuroscience, 2016, 9: 77(IF=5.4)8. Wen-Ling Dai, Feng Xiong, Bing Yan, Zheng-Yu Cao, Wen-Tao Liu*, Ji-Hua Liu*, Bo-Yang Yu, Blockade of neuronal dopamine D2 receptor attenuates morphine tolerance in mice spinal cord, Scientific Reports, 2016, 6: 38746(IF=5.1)9. Pan YB, Sun XD, Jiang L, Hu L, Kong H, Han Y, Qian C, Song C, Qian YN, Liu WT*, Metformin reduces morphine tolerance by inhibiting microglial-mediated neuroinflammation, Journal of Neuroinflammation, 2016, 13(1): 294(IF=5.1)10. Lu LJ#, Pan CL#, Chen L, Hu L, Wang CY, Han Y, Yang YJ*, Cheng ZX*, Liu WT*, AMPK activation by peri-sciatic nerve administration of ozone attenuates CCI-induced neuropathic pain in rats, Journal of Molecular Cell Biology, 2016, 1-12(IF=6.5)11. Cai Y, Kong H, Pan YB, Jiang L, Pan XX, Hu L, Qian YN, Jiang CY*, Liu WT*, Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia, Journal of Neuroinflammation, 2016, 13: 53(IF=5.1)12. Li JJ, Xu LJ, Deng XT, Jiang CY, Pan CL, Chen L, Han Y, Dai WL, Hu L, Zhang GQ, Cheng ZX, Liu WT*, N-acetyl-cysteine attenuates neuropathic pain by suppressing matrix metalloproteinases, Pain, 2016, 157(8): 1711-1723(IF=5.8)13. Song HY, Han Y, Pan CL, Deng XT, Dai WL, Hu L, Jiang CY, Yang YJ, Cheng ZX, Li F, Zhang GQ, Wu XF, Liu WT*, Activation of adenosine monophosphate-activated protein kinase suppresses neuroinflammation and ameliorates bone cancer pain: involvement of inhibition on mitogen-activated protein kinase, Anesthesiology, 2015, 123(5): 1170-1185(IF=5.8)"