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H

Henry A. Lester

california institute of technology

98H-index
470Paper Count
3.2WCitation Count
Published Papers 169
Publication Date
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Targeted Mutations Activate Allosteric Modulation of α5-Containing Nicotinic Acetylcholine Receptors
errACS Chemical Neuroscience
IF3.9
err2026-06-04
err0
errOAAI
errChristopher B. Marotta; Henry A. Lester; Dennis A. Dougherty
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Hydrogel Encapsulation of a Designed Fluorescent Protein Biosensor for Continuous Measurements of Sub-100 nM Nicotine
errACS APPLIED BIO MATERIALS
IF4.7
err2025-12-01
err0
PREAI
errNichols, Aaron L.; Marotta, Christopher B.; Frisenhahn, Nicholas J.; Dalfonzo, Sophia R.; Muthusamy, Anand; Wagenaar, Daniel A.; Mayo, Stephen L.; Dougherty, Dennis A.; Lester, Henry A.
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Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda
errNICOTINE & TOBACCO RESEARCH
IF3
err2025-03-13
err0
PREAI
errAaron L Nichols; Christopher B Marotta; Heather Lukas; Nicholas J Friesenhahn; Daniel A Wagenaar; Stephen L Mayo; Dennis A Dougherty; Neal L Benowitz; Wei Gao; Anand K Muthusamy; Henry A Lester
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Simulating early steps in nicotine dependence: Pharmacokinetics, activation, and chaperoning of nicotinic receptors
errMOLECULAR PHARMACOLOGY
IF3
err2025-01-01
err1
PREAI
errWang, Alexander Z.; Jeon, Janice; Drenan, Ryan M.; Lester, Henry A.
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errSave
Antidepressants enter cells, organelles, and membranes
errNEUROPSYCHOPHARMACOLOGY
IF7.1
err2023-10-02
err1
errOAAI
errBlumenfeld, Zack; Bera, Kallol; Castren, Eero; Lester, Henry A.
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errSave
Human α6β4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site
errMOLECULAR PHARMACOLOGY
IF3
err2023-06-01
err2
PREAI
errMaldifassi, Maria Constanza; Campello, Hugo Rego; Gallagher, Timothy; Lester, Henry A.; Dougherty, Dennis A.
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errSave
Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands (vol 11, e74648, 2022)
errELIFE
IF0
err2022-12-15
err0
errOAAI
errNichols, Aaron L.; Blumenfeld, Zack; Fan, Chengcheng; Luebbert, Laura; Blom, Annet E. M.; Cohen, Bruce N.; Marvin, Jonathan S.; Borden, Philip M.; Kim, Charlene H.; Muthusamy, Anand K.; Shivange, Amol V.; Knox, Hailey J.; Campello, Hugo Rego; Wang, Jonathan H.; Dougherty, Dennis A.; Looger, Loren L.; Gallagher, Timothy; Rees, Douglas C.; Lester, Henry A.
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errSave
How many SARS-CoV-2 viroporins are really ion channels?
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-08-25
err13
errOAAI
errHarrison, Neil L.; Abbott, Geoffrey W.; Gentzsch, Martina; Aleksandrov, Andrei; Moroni, Anna; Thiel, Gerhard; Grant, Stephen; Nichols, Colin G.; Lester, Henry A.; Hartel, Andreas; Shepard, Kenneth; Garcia, David Cabrera; Yazawa, Masayuki
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Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-08-25
err9
PREAI
errKnox, Hailey J.; Campello, Hugo Rego; Lester, Henry A.; Gallagher, Timothy; Dougherty, Dennis A.
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errSave
Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-04-21
err7
errOAAI
errMuthusamy, Anand K.; Kim, Charlene H.; Virgil, Scott C.; Knox, Hailey J.; Marvin, Jonathan S.; Nichols, Aaron L.; Cohen, Bruce N.; Dougherty, Dennis A.; Looger, Loren L.; Lester, Henry A.
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errSave
Regulation of epithelial sodium channel activity by SARS-CoV-1 and SARS-CoV-2 proteins
errBIOPHYSICAL JOURNAL
IF3.1
err2021-07-01
err21
errOAAI
errGrant, Stephen N.; Lester, Henry A.
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errSave
Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: nothing but good news?
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2020-10-19
err2
errOAAI
errGrant, Stephen; Lester, Henry A.
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errSave
Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2019-11-12
err12
errOAAI
errBera, Kallol; Kamajaya, Aron; Shivange, Amol, V; Muthusamy, Anand K.; Nichols, Aaron L.; Borden, Philip M.; Grant, Stephen; Jeon, Janice; Lin, Elaine; Bishara, Ishak; Chin, Theodore M.; Cohen, Bruce N.; Kim, Charlene H.; Unger, Elizabeth K.; Tian, Lin; Marvin, Jonathan S.; Looger, Loren L.; Lester, Henry A.
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errSave
Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem
errNEURON
IF15
err2019-11-01
err1
errOAAI
errLester, Henry A.; Dougherty, Dennis A.
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errSave
Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2019-10-28
err7
errOAAI
errMulcahy, Matthew J.; Huard, Stephanie M.; Paulo, Joao A.; Wang, Jonathan H.; McKinney, Sheri; Henderson, Brandon J.; Lester, Henry A.
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errSave
Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-09-13
err23
errOAAI
errBlom, Annet E. M.; Campello, Hugo Rego; Lester, Henry A.; Gallagher, Timothy; Dougherty, Dennis A.
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errSave
Chronic Menthol Does Not Change Stoichiometry or Functional Plasma Membrane Levels of Mouse α3β4-Containing Nicotinic Acetylcholine Receptors
errMOLECULAR PHARMACOLOGY
IF3
err2019-04-01
err2
errOAAI
errBavan, Selvan; Kim, Charlene H.; Henderson, Brandon J.; Lester, Henry A.
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errSave
Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2019-02-04
err54
errOAAI
errShiyange, Amol, V; Borden, Philip M.; Muthusamy, Anand K.; Nichols, Aaron L.; Bera, Kailo; Bao, Huan; Bishara, Ishak; Jeon, Janice; Mulcahy, Matthew J.; Cohen, Bruce; O'Riordan, Saidhbhe L.; Kim, Charlene; Dougherty, Dennis A.; Chapman, Edwin R.; Marvin, Jonathan S.; Looger, Loren L.; Lester, Henry A.
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errSave
Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein
errNEUROBIOLOGY OF DISEASE
IF5.6
err2018-09-01
err29
errOAAI
errSubramaniam, Sudhakar R.; Magen, Iddo; Bove, Nicholas; Zhu, Chunni; Lemesre, Vincent; Dutta, Garima; Elias, Chris Jean; Lester, Henry A.; Chesselet, Marie-Francoise
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errSave
α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor
errACS CHEMICAL BIOLOGY
IF3.8
err2018-07-30
err8
errOAAI
errNichols, Aaron L.; Noridomi, Kaori; Hughes, Christopher R.; Jalali-Yazdi, Farzad; Eaton, J. Brek; Lan Huong Lai; Advani, Gaurav; Lukas, Ronald J.; Lester, Henry A.; Chen, Lin; Roberts, Richard W.
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Research Directions

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