logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
N

Nikolaos G. Sgourakis

children's hospital of philadelphia

33H-index
151Paper Count
4.8KCitation Count
Published Papers 59
Publication Date
logo
Ready-to-load MHC-I nanoparticles for high-throughput T cell screening studies
errScience Advances
IF12.5
err2026-06-12
err0
errOAAI
errHoang Anh T. Phan; Soomin Eom; Daniel Hwang; Michael C. Young; Shirley M. Sun; Molly C. Erdman; Yi Sun; Leena Mallik; Photis Rotsides; Mark M. Painter; E. John Wherry; Dimitri S. Monos; Nikolaos G. Sgourakis
errShare
errSave
Engineering high-fidelity tapasin variants to enhance MHC-I antigen presentation
errJournal of Biological Chemistry
IF3.9
err2026-03-21
err0
errOAAI
errMolly C. Erdman; Kaya Epstein; Daniel Hwang; Radia M.M. Khan; Shirley M. Sun; Nikolaos G. Sgourakis
errShare
errSave
HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors
errSCIENCE ADVANCES
IF12.5
err2026-01-01
err0
PREAI
errHwang, Daniel; Erdman, Molly C.; Adhikari, Santosh; Pantula, Ram; Epstein, Kaya; Li, Peiyao; Costabile, Francesca; Rotsides, Photis; Wang, Chloe S.; Sun, Shirley M.; Fazelinia, Hossein; Spruce, Lynn A.; Fugmann, Tim; Rrustemi, Trendelina; Soh, Wai Tuck; Farrel, Alvin; Want, Muzamil Y.; Facciabene, Andrea; Mir, Mustafa; Maris, John M.; Sgourakis, Nikolaos G.
errShare
errSave
Atomically accurate de novo design of antibodies with RFdiffusion
errNature
IF48.5
err2025-11-05
err0
errOAAI
errNathaniel R. Bennett; Joseph L. Watson; Robert J. Ragotte; Andrew J. Borst; DéJenaé L. See; Connor Weidle; Riti Biswas; Yutong Yu; Ellen L. Shrock; Russell Ault; Philip J. Y. Leung; Buwei Huang; Inna Goreshnik; John Tam; Kenneth D. Carr; Benedikt Singer; Cameron Criswell; Basile I. M. Wicky; Dionne Vafeados; Mariana Garcia Sanchez; Ho Min Kim; Susana Vázquez Torres; Sidney Chan; Shirley M. Sun; Timothy T. Spear; Yi Sun; Keelan O’Reilly; John M. Maris; Nikolaos G. Sgourakis; Roman A. Melnyk; Chang C. Liu; David Baker
errShare
errSave
A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens
errStructure
IF4.3
err2025-07-18
err0
PREAI
errSagar Gupta; Nikolaos G. Sgourakis
errShare
errSave
Dynamic sampling of a surveillance state enables DNA proofreading by Cas9
errCELL CHEMICAL BIOLOGY
IF7.2
err2025-02-01
err0
PREAI
errDe Paula, Viviane S.; Dubey, Abhinav; Arthanari, Haribabu; Sgourakis, Nikolaos G.
errShare
errSave
Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network
errJOURNAL OF MOLECULAR BIOLOGY
IF4.5
err2025-01-01
err0
errOAAI
errWoodward, Claire H.; Solieva, Shahlo O.; Hwang, Daniel; Paula, Viviane S. De; Fabilane, Charina S.; Young, Michael C.; Trent, Tony; Teeley, Ella C.; Majumdar, Ananya; Spangler, Jamie B.; Bowman, Gregory R.; Sgourakis, Nikolaos G.
errShare
errSave
Targeting peptide antigens using a multiallelic MHC I-binding system
errNATURE BIOTECHNOLOGY
IF41.7
err2024-12-13
err1
errOAAI
errDu, Haotian; Mallik, Leena; Hwang, Daniel; Sun, Yi; Kaku, Chengzi; Hoces, Daniel; Sun, Shirley M.; Ghinnagow, Reem; Carro, Stephen D.; Phan, Hoang Anh T.; Gupta, Sagar; Blackson, Wyatt; Lee, Hyejin; Choe, Christian A.; Dersh, Devin; Liu, Jingjia; Bell, Braxton; Yang, Hongli; Papadaki, Georgia F.; Young, Michael C.; Zhou, Emily; El Nesr, Gina; Goli, Kimia Dasteh; Eisenlohr, Laurence C.; Minn, Andy J.; Hernandez-Lopez, Rogelio A.; Jardine, Joseph G.; Sgourakis, Nikolaos G.; Huang, Po-Ssu
errShare
errSave
Exploring engineered HLA-I chaperones for enhancing the immunogenicity of cold tumors
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errHwang, Daniel; Sun, Shirley; Sgourakis, Nikolaos
errShare
errSave
The Virtual Child
errCANCER DISCOVERY
IF33.3
err2024-04-04
err1
errOAAI
errGilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M.
errShare
errSave
Expanding the applications of open MHC-I molecules for enhanced thermostability and peptide loading to HLA-A*11:01 and HLA-C*07:02 allotypes
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errOnwuka, Amarachi; Sun, Yi; Young, Michael; Sgourakis, Nikolaos
errShare
errSave
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
errNATURE COMMUNICATIONS
IF15.7
err2023-12-11
err3
errOAAI
errMcShan, Andrew C.; Flores-Solis, David; Sun, Yi; Garfinkle, Samuel E.; Toor, Jugmohit S.; Young, Michael C.; Sgourakis, Nikolaos G.
errShare
errSave
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
errSCIENCE IMMUNOLOGY
IF16.3
err2023-12-01
err3
errOAAI
errSun, Yi; Florio, Tyler J.; Gupta, Sagar; Young, Michael C.; Marshall, Quinlen F.; Garfinkle, Samuel E.; Papadaki, Georgia F.; Truong, Hau V.; Mycek, Emily; Li, Peiyao; Farrel, Alvin; Church, Nicole L.; Jabar, Shereen; Beasley, Matthew D.; Kiefel, Ben R.; Yarmarkovich, Mark; Mallik, Leena; Maris, John M.; Sgourakis, Nikolaos G.
errShare
errSave
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
errNATURE COMMUNICATIONS
IF15.7
err2023-10-10
err11
errOAAI
errGupta, Sagar; Nerli, Santrupti; Kandy, Sreeja Kutti; Mersky, Glenn L.; Sgourakis, Nikolaos G.
errShare
errSave
A Chicken Tapasin ortholog can chaperone empty HLA-B*37:01 molecules independent of other peptide-loading components
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-10-01
err2
errOAAI
errPapadaki, Georgia F.; Woodward, Claire H.; Young, Michael C.; Winters, Trenton J.; Burslem, George M.; Sgourakis, Nikolaos G.
errShare
errSave
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-06-13
err7
errOAAI
errSun, Yi; Young, Michael C.; Woodward, Claire H.; Danon, Julia N.; Truong, Hau, V; Gupta, Sagar; Winters, Trenton J.; Font-Burgada, Joan; Burslem, George M.; Sgourakis, Nikolaos G.
errShare
errSave
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
errSCIENCE ADVANCES
IF12.5
err2023-02-24
err10
errOAAI
errSun, Yi; Papadaki, Georgia F.; Devlin, Christine A.; Danon, Julia N.; Young, Michael C.; Winters, Trenton J.; Burslem, George M.; Procko, Erik; Sgourakis, Nikolaos G.
errShare
errSave
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-01-25
err5
errOAAI
errPapadaki, Georgia F.; Ani, Omar; Florio, Tyler J.; Young, Michael C.; Danon, Julia N.; Sun, Yi; Dersh, Devin; Sgourakis, Nikolaos G.
errShare
errSave
Structural classification of peptide-HLA complexes enables accurate high-throughput modeling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errGupta, Sagar; Nerli, Santrupti; Kandy, Sreeja Kutti; Mersky, Glenn; Sgourakis, Nikolaos
errShare
errSave
Inspiring new NRPS cyclization domain mechanisms: the role of protein dynamics in substrate recognition and allostery
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errMarincin, Kenneth; Mishra, Subrata; Kancherla, Aswani; Bouivignies, Guillaume; Nerli, Santrupti; Sgourakis, Nikolaos; Dowling, Daniel; Frueh, Dominique
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
D
David Haussler
H-index: 175 · Papers: 720
S
Stefan M. Pfister
H-index: 159 · Papers: 2.1K
A
Ad Bax
H-index: 145 · Papers: 626
E
E. John Wherry
H-index: 142 · Papers: 638
W
William F. DeGrado
H-index: 124 · Papers: 758
View more