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Novel GABAAR antagonists target networked gene hubs at the leading-edge in high-grade gliomas Shard, Chloe; Jones, Anya; Fouladzadeh, Anahita; Palethorpe, Helen; Francis, Abbie; Boyle, Yasmin; Dewdney, Brittany; Yeow, Yen; Mahajan, Ishika; Barker, Matthew; Kuznetsova, Irina; Jones, Matthew; Patil, Ashwini; Ormsby, Rebecca; Rezaeiravesh, Sara; Ng, Zi Ying; Poonnoose, Santosh; Bosco, Anthony; Valvi, Santosh; Forrest, Alistair; Johns, Terrance; Gomez, Guillermo; Fletcher, Emily Share Save
connectomeDB2025: a rigorously curated, multi-species resource of experimentally supported ligand-receptor interactions Liu, Peiwen; Maezono, Sakura Eri B.; Lin, Weitao; Yeow, Yen; Liu, Ya-Yu; Hisham, Yasmin; Hou, Rui; Ramilowski, Jordan A.; Forrest, Alistair R. R. Share Save
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Interleukin-4 modulates type I interferon to augment antitumor immunity Newnes, Hannah V.; Armitage, Jesse D.; Buzzai, Anthony C.; de Jong, Emma; Audsley, Katherine M.; Barnes, Samantha A.; Srinivasan, Shamini; Serralha, Michael; Fear, Vanessa S.; Guo, Belinda B.; Jones, Matt E.; Forrest, Alistair R. R.; Foley, Bree; Darcy, Phil K.; Beavis, Paul A.; Bosco, Anthony; Waithman, Jason Share Save
MicroRNA-142-3p Overcomes Drug Resistance in Hepatocellular Carcinoma by Targeting YES1 and TWF1 Mahboobnia, Khadijeh; Kabir, Tasnuva D.; Hou, Rui; Liu, Peiwen; Forrest, Alistair; Beveridge, Dianne J.; Richardson, Kirsty L.; Stuart, Lisa M.; Yeoh, George C.; Leedman, Peter J. Share Save
Pericyte phenotype switching alleviates immunosuppression and sensitizes vascularized tumors to immunotherapy in preclinical models Li, Zhi-Jie; He, Bo; Domenichini, Alice; Satiaputra, Jiulia; Wood, Kira H.; Lakhiani, Devina D.; Bashaw, Abate A.; Nilsson, Lisa M.; Li, Ji; Bastow, Edward R.; Johansson-Percival, Anna; Denisenko, Elena; Forrest, Alistair R. R.; Sakaram, Suraj; Carretero, Rafael; Haemmerling, Guenter J.; Nilsson, Jonas A.; Lee, Gabriel Y. F.; Ganss, Ruth Share Save
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes Kidman, Joel; Zemek, Rachael M.; Sidhom, John-William; Correa, Debora; Principe, Nicola; Sheikh, Fezaan; Fear, Vanessa S.; Forbes, Catherine A.; Chopra, Abha; Boon, Louis; Zaitouny, Ayham; de Jong, Emma; Holt, Robert A.; Jones, Matt; Millward, Michael J.; Lassmann, Timo; Forrest, Alistair R. R.; Nowak, Anna K.; Watson, Mark; Lake, Richard A.; Lesterhuis, W. Joost; Chee, Jonathan Share Save
Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones Denisenko, Elena; de Kock, Leanne; Tan, Adeline; Beasley, Aaron B.; Beilin, Maria; Jones, Matthew E.; Hou, Rui; Muiri, Daithi o; Bilic, Sanela; Mohan, G. Raj K. A.; Salfinger, Stuart; Fox, Simon; Hmon, Khaing P. W.; Yeow, Yen; Kim, Youngmi; John, Rhea; Gilderman, Tami S.; Killingbeck, Emily; Gray, Elin S.; Cohen, Paul A.; Yu, Yu; Forrest, Alistair R. R. Share Save
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC Boslem, Ebru; Reibe, Saskia; Carlessi, Rodrigo; Smeuninx, Benoit; Tegegne, Surafel; Egan, Casey L.; Mclennan, Emma; Terry, Lauren V.; Nobis, Max; Mu, Andre; Nowell, Cameron; Horadagoda, Neil; Mellett, Natalie A.; Timpson, Paul; Jones, Matthew; Denisenko, Elena; Forrest, Alistair R. R.; Tirnitz-Parker, Janina E. E.; Meikle, Peter J.; Rose-John, Stefan; Karin, Michael; Febbraio, Mark A. Share Save
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential Carlessi, Rodrigo; Denisenko, Elena; Boslem, Ebru; Kohn-Gaone, Julia; Main, Nathan; Abu Bakar, N. Dianah B.; Shirolkar, Gayatri D.; Jones, Matthew; Beasley, Aaron B.; Poppe, Daniel; Dwyer, Benjamin J.; Jackaman, Connie; Tijam, M. Christian; Lister, Ryan; Karin, Michael; Fallowfield, Jonathan A.; Kendall, Timothy J.; Forbes, Stuart J.; Gray, Elin S.; Olynyk, John K.; Yeoh, George; Forrest, Alistair R. R.; Ramm, Grant A.; Febbraio, Mark A.; Tirnitz-Parker, Janina E. E. Share Save
Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice Zemek, Rachael M.; Chin, Wee Loong; Fear, Vanessa S.; Wylie, Ben; Casey, Thomas H.; Forbes, Cath; Tilsed, Caitlin M.; Boon, Louis; Guo, Belinda B.; Bosco, Anthony; Forrest, Alistair R. R.; Millward, Michael J.; Nowak, Anna K.; Lake, Richard A.; Lassmann, Timo; Lesterhuis, W. Joost Share Save
Deep sequencing of short capped RNAs reveals novel families of noncoding RNAs de Hoon, Michiel; Bonetti, Alessandro; Plessy, Charles; Ando, Yoshinari; Hon, Chung-Chau; Ishizu, Yuri; Itoh, Masayoshi; Kato, Sachi; Lin, Dongyan; Maekawa, Sho; Murata, Mitsuyoshi; Nishiyori, Hiromi; Shin, Jay W.; Stolte, Jens; Suzuki, Ana Maria; Tagami, Michihira; Takahashi, Hazuki; Forrest, Alistair R. R.; Hayashizaki, Yoshihide; Kere, Juha; Carninci, Piero; Thongjuea, Supat Share Save
Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis Cabrera-Serrano, Macarena; Caccavelli, Laure; Savarese, Marco; Vihola, Anna; Jokela, Manu; Johari, Mridul; Capiod, Thierry; Madrange, Marine; Bugiardini, Enrico; Brady, Stefen; Quinlivan, Rosaline; Merve, Ashirwad; Scalco, Renata; Hilton-Jones, David; Houlden, Henry; Aydin, Halil Ibrahim; Ceylaner, Serdar; Drewes, Sarah; Vockley, Jerry; Taylor, Rhonda L.; Folland, Chiara; Kelly, Aasta; Goullee, Hayley; Ylikallio, Emil; Auranen, Mari; Tyynismaa, Henna; Udd, Bjarne; Forrest, Alistair R. R.; Davis, Mark R.; Bratkovic, Drago; Manton, Nicholas; Robertson, Thomas; O'Gorman, Cullen; McCombe, Pamela; Laing, Nigel G.; Phillips, Liza; de Lonlay, Pascale; Ravenscroft, Gianina Share Save
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Molecular Insights Into Regulatory T-Cell Adaptation to Self, Environment, and Host Tissues: Plasticity or Loss of Function in Autoimmune Disease Brown, Cheryl Y.; Sadlon, Timothy; Hope, Christopher M.; Wong, Ying Y.; Wong, Soon; Liu, Ning; Withers, Holly; Brown, Katherine; Bandara, Veronika; Gundsambuu, Batjargal; Pederson, Stephen; Breen, James; Robertson, Sarah Anne; Forrest, Alistair; Beyer, Marc; Barry, Simon Charles Share Save
Functional annotation of human long noncoding RNAs via molecular phenotyping (vol 30, pg 1060, 2020) Ramilowski, Jordan A.; Yip, Chi Wai; Agrawal, Saumya; Chang, Jen-Chien; Ciani, Yari; Kulakovskiy, Ivan V.; Mendez, Mickael; Ooi, Jasmine Li Ching; Ouyang, John F.; Parkinson, Nick; Petri, Andreas; Roos, Leonie; Severin, Jessica; Yasuzawa, Kayoko; Abugessaisa, Imad; Akalin, Altuna; Antonov, Ivan V.; Arner, Erik; Bonetti, Alessandro; Bono, Hidemasa; Borsari, Beatrice; Brombacher, Frank; Cameron, Christopher J. F.; Cannistraci, Carlo Vittorio; Cardenas, Ryan; Cardon, Melissa; Chang, Howard; Dostie, Josee; Ducoli, Luca; Favorov, Alexander; Fort, Alexandre; Garrido, Diego; Gil, Noa; Gimenez, Juliette; Guler, Reto; Handoko, Lusy; Harshbarger, Jayson; Hasegawa, Akira; Hasegawa, Yuki; Hashimoto, Kosuke; Hayatsu, Norihito; Heutink, Peter; Hirose, Tetsuro; Imada, Eddie L.; Itoh, Masayoshi; Kaczkowski, Bogumil; Kanhere, Aditi; Kawabata, Emily; Kawaji, Hideya; Kawashima, Tsugumi; Kelly, S. Thomas; Kojima, Miki; Kondo, Naoto; Koseki, Haruhiko; Kouno, Tsukasa; Kratz, Anton; Kurowska-Stolarska, Mariola; Kwon, Andrew Tae Jun; Leek, Jeffrey; Lennartsson, Andreas; Lizio, Marina; Lopez-Redondo, Fernando; Luginbuhl, Joachim; Maeda, Shiori; Makeev, Vsevolod J.; Marchionni, Luigi; Medvedeva, Yulia A.; Minoda, Aki; Muller, Ferenc; Munoz-Aguirre, Manuel; Murata, Mitsuyoshi; Nishiyori, Hiromi; Nitta, Kazuhiro R.; Noguchi, Shuhei; Noro, Yukihiko; Nurtdinov, Ramil; Okazaki, Yasushi; Orlando, Valerio; Paquette, Denis; Parr, Callum J. C.; Rackham, Owen J. L.; Rizzu, Patrizia; Martinez, Diego Fernando Sanchez; Sandelin, Albin; Sanjana, Pillay; Semple, Colin A. M.; Shibayama, Youtaro; Sivaraman, Divya M.; Suzuki, Takahiro; Szumowski, Suzannah C.; Tagami, Michihira; Taylor, Martin S.; Terao, Chikashi; Thodberg, Malte; Thongjuea, Supat; Tripathi, Vidisha; Ulitsky, Igor; Verardo, Roberto; Vorontsov, Ilya E.; Yamamoto, Chinatsu; Young, Robert S.; Baillie, J. Kenneth; Forrest, Alistair R. R.; Guigo, Roderic; Hoffman, Michael M.; Hon, Chung Chau; Kasukawa, Takeya; Kauppinen, Sakari; Kere, Juha; Lenhard, Boris; Schneider, Claudio; Suzuki, Harukazu; Yagi, Ken; de Hoon, Michiel J. L.; Shin, Jay W.; Carninci, Piero Share Save
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer Wu, Sunny Z.; Roden, Daniel L.; Wang, Chenfei; Holliday, Holly; Harvey, Kate; Cazet, Aurelie S.; Murphy, Kendelle J.; Pereira, Brooke; Al-Eryani, Ghamdan; Bartonicek, Nenad; Hou, Rui; Torpy, James R.; Junankar, Simon; Chan, Chia-Ling; Lam, Chuan En; Hui, Mun N.; Gluch, Laurence; Beith, Jane; Parker, Andrew; Robbins, Elizabeth; Segara, Davendra; Mak, Cindy; Cooper, Caroline; Warrier, Sanjay; Forrest, Alistair; Powell, Joseph; O'Toole, Sandra; Cox, Thomas R.; Timpson, Paul; Lim, Elgene; Liu, X. Shirley; Swarbrick, Alexander Share Save
Functional annotation of human long noncoding RNAs via molecular phenotyping Ramilowski, Jordan A.; Yip, Chi Wai; Agrawal, Saumya; Chang, Jen-Chien; Ciani, Yari; Kulakovskiy, Ivan V.; Mendez, Mickael; Ooi, Jasmine Li Ching; Ouyang, John F.; Parkinson, Nick; Petri, Andreas; Roos, Leonie; Severin, Jessica; Yasuzawa, Kayoko; Abugessaisa, Imad; Akalin, Altuna; Antonov, Ivan V.; Arner, Erik; Bonetti, Alessandro; Bono, Hidemasa; Borsari, Beatrice; Brombacher, Frank; Cameron, Chris J. F.; Cannistraci, Carlo Vittorio; Cardenas, Ryan; Cardon, Melissa; Chang, Howard; Dostie, Josee; Ducoli, Luca; Favorov, Alexander; Fort, Alexandre; Garrido, Diego; Gil, Noa; Gimenez, Juliette; Guler, Reto; Handoko, Lusy; Harshbarger, Jayson; Hasegawa, Akira; Hasegawa, Yuki; Hashimoto, Kosuke; Hayatsu, Norihito; Heutink, Peter; Hirose, Tetsuro; Imada, Eddie L.; Itoh, Masayoshi; Kaczkowski, Bogumil; Kanhere, Aditi; Kawabata, Emily; Kawaji, Hideya; Kawashima, Tsugumi; Kelly, S. Thomas; Kojima, Miki; Kondo, Naoto; Koseki, Haruhiko; Kouno, Tsukasa; Kratz, Anton; Kurowska-Stolarska, Mariola; Kwon, Andrew Tae Jun; Leek, Jeffrey; Lennartsson, Andreas; Lizio, Marina; Lopez-Redondo, Fernando; Luginbuhl, Joachim; Maeda, Shiori; Makeev, Vsevolod J.; Marchionni, Luigi; Medvedeva, Yulia A.; Minoda, Aki; Mueller, Ferenc; Munoz-Aguirre, Manuel; Murata, Mitsuyoshi; Nishiyori, Hiromi; Nitta, Kazuhiro R.; Noguchi, Shuhei; Noro, Yukihiko; Nurtdinov, Ramil; Okazaki, Yasushi; Orlando, Valerio; Paquette, Denis; Parr, Callum J. C.; Rackham, Owen J. L.; Rizzu, Patrizia; Martinez, Diego Fernando Sanchez; Sandelin, Albin; Sanjana, Pillay; Semple, Colin A. M.; Shibayama, Youtaro; Sivaraman, Divya M.; Suzuki, Takahiro; Szumowski, Suzannah C.; Tagami, Michihira; Taylor, Martin S.; Terao, Chikashi; Thodberg, Malte; Thongjuea, Supat; Tripathi, Vidisha; Ulitsky, Igor; Verardo, Roberto; Vorontsov, Ilya E.; Yamamoto, Chinatsu; Young, Robert S.; Baillie, J. Kenneth; Forrest, Alistair R. R.; Guigo, Roderic; Hoffman, Michael M.; Hon, Chung Chau; Kasukawa, Takeya; Kauppinen, Sakari; Kere, Juha; Lenhard, Boris; Schneider, Claudio; Suzuki, Harukazu; Yagi, Ken; de Hoon, Michiel J. L.; Shin, Jay W.; Carninci, Piero Share Save
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