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Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension Al-Qazazi, Ruaa; Emon, Isaac M.; Potus, Francois; Martin, Ashley Y.; Lima, Patricia D. A.; Vlasschaert, Caitlyn; Ott, Benjamin P.; Chen, Kuang-Hueih; Wu, Danchen; Dasgupta, Asish; Noordhof, Curtis; Jefferson, Lindsay; Buttigieg, Marco M.; Mcnaughton, Amy J. M.; Hindmarch, Charles C. T.; Bick, Alexander G.; Nichols, William C.; Chung, Wendy K.; Hassoun, Paul M.; Damico, Rachel L.; Zhu, Na; Shen, Yufeng; Rauh, Michael J.; Archer, Stephen L. Share Save
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Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies Lemay, Sarah-Eve; Mougin, Manon; Sauvaget, Melanie; El Kabbout, Reem; Valasarajan, Chanil; Yamamoto, Keiko; Martineau, Sandra; Pelletier, Andreanne; Bilodeau, Coralie; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Breuils-Bonnet, Sandra; Montesinos, Monica S.; Lu, Min; Chen, Huidong; Gilbert, Megan; Theberge, Charlie; Potus, Francois; Pullamsetti, Soni; Provencher, Steeve; Bonnet, Sebastien; Boucherat, Oliver Share Save
ATP citrate lyase drives vascular remodeling in systemic and pulmonary vascular diseases through metabolic and epigenetic changes Grobs, Yann; Romanet, Charlotte; Lemay, Sarah-Eve; Bourgeois, Alice; Voisine, Pierre; Theberge, Charlie; Sauvaget, Melanie; Breuils-Bonnet, Sandra; Martineau, Sandra; El Kabbout, Reem; Valasarajan, Chanil; Chelladurai, Prakash; Pelletier, Andreanne; Mougin, Manon; Dumais, Elizabeth; Perron, Jean; Flamand, Nicolas; Potus, Francois; Provencher, Steeve; Pullamsetti, Soni Savai; Boucherat, Olivier; Bonnet, Sebastien Share Save
Integrin α5β1 represents a novel therapeutic target to improve vascular remodeling in pulmonary arterial hypertension Lemay, Sarah-Eve; Montesinos, Monica; Grobs, Yann; Yokokawa, Tetsuro; Shimauchi, Tsukasa; Romanet, Charlotte; Sauvaget, Melanie; Bonnet, Sandra Breuils; Bourgeois, Alice; Theberge, Charlie; Martineau, Sandra; Lippa, Blaise; Goodwin, Bryan; Lin, Albert; Wang, Hua; Dowling, James; Lu, Min; Qiao, Qi; McTeague, T. Andrew; Moy, Terence I.; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Development and characterization of an ex vivo human precision-cut lung slice (hPCLS) system for target validation for pulmonary arterial hypertension Kim, Haejin; Jain, Dhawal; Akram, Muzaffar; Zhou, Willa; Provencher, Steeve; Lemay, Sarah-Eve; Bonnet, Sebastien; Potus, Francois; Montesinos, Monica; Lu, Min; Goodwin, Bryan Share Save
Integrin α5β1 contributes to pathological remodeling of the right ventricle in pulmonary arterial hypertension Lemay, Sarah-Eve; Montesinos, Monica; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Sauvaget, Melanie; Bonnet, Sandra Breuils; Theberge, Charlie; Martineau, Sandra; Lippa, Blaise; Goodwin, Bryan; Lin, Albert; Wang, Hua; Dowling, James; Lu, Min; Qiao, Qi; McTeague, T. Andrew; Moy, Terence I.; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Targeting ATP Citrate Lyase: A Novel Therapeutic Strategy for Vascular Remodeling in Pulmonary Hypertension Grobs, Yann; Romanet, Charlotte; Lemay, Sarah-Eve; Bourgeois, Alice; Voisine, Pierre; Theberge, Charlie; Sauvaget, Melanie; Bonnet, Sandra Breuils; Martineau, Sandra; Reem, EL-Kabbout; Pelletier, Andreanne; Mougin, Manon; Dumais, Elizabeth; Perron, Jean; Flamand, Nicolas; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Targeting NEK2 to Induce Senescence and DNA Damage in Pulmonary Arterial Hypertension Martineau, Sandra; Yamamoto, Keiko; Bourgeois, Alice; Lemay, Sarah-Eve; Sauvaget, Melanie; Breuils, Sandra Bonnet; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Targeting Aurora Kinase B Improves Vascular Remodeling in Pulmonary Arterial Hypertension Lemay, Sarah-Eve; Mougin, Manon; Sauvaget, Melanie; Reem, EL-Kabbout; Valasarajan, Chanil; Yamamoto, Keiko; Martineau, Sandra; Pelletier, Andreanne; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Bonnet, Sandra Breuils; Montesinos, Monica; Lu, Min; Chen, Huidong; Theberge, Charlie; Potus, Francois; Pullamsetti, Soni Savai; Provencher, Steeve; Bonnet, Sebastien; Boucherat, Olivier Share Save
Treatment of pulmonary arterial hypertension by blocking integrin a5b1, a potential disease-modifying strategy Montesinos, Monica; Lemay, Sarah-Eve; Kapoor, Parmita; Rapisardi, Hailey; Minh Hai Nguyen; Kim, Haejin; Akram, Muzaffar; Jain, Dhawal; Konopka, Elizabeth; Moy, Terence I.; Smukste, Inese; McTeague, T. Andrew; Dowling, James; Lama, Sujan; Pondish, Jessica; Qiao, Qi; Monroy, Meghan Monroy; Lin, Albert; Wang, Hua; Boucherat, Olivier; Sauvaget, Melanie; Potus, Francois; Breuils, Sandra; Theberge, Charlie; Provencher, Steeve; Ray, Adrian; Lippa, Blaise; Bonnet, Sebastien; Goodwin, Bryan; Lu, Min Share Save
Upregulation of Dynamin 2 (DNM2) Increases Mitochondrial Fission and Cell Proliferation in Pulmonary Arterial Hypertension Das Gupta, Asish; Chen, Kuang-Hueih; Wu, Danchen; Lima, Patricia; Martin, Ashley; Mewburn, Jeffrey; Al-Qazazi, Ruaa; Emon, Isaac; Colpman, Pierce; Yerramilli, Siddartha; Jones, Oliver; Hindmarch, Charles; Potus, Francois; Bonnet, Sebastien; Archer, Stephen Share Save
Clonal Hematopoiesis of Indeterminant Potential is Associated with Pulmonary Arterial Hypertension Emon, Isaac; Al-Qazazi, Ruaa; Rauh, Michael; Vlasschaert, Caitlyn; Ott, Benjamin; McNaughton, Amy; Potus, Francois; Pauciulo, Michael; Bick, Alexander; Nichols, William; Chung, Wendy; Archer, Stephen Share Save
Exploring P300/CBP as therapeutic approach for right ventricular dysfunction in PAH Bourgeois, Alice; Lemay, Sarah-Eve; Grobs, Yann; Theberge, Charlie; Sauvaget, Melanie; Martineau, Sandra; Gilbert, Megan; Bonnet, Sandra Breuils; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
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Aurora kinase B: A New Therapeutic Target in PAH Lemay, Sarah-Eve; Mougin, Manon; Sauvaget, Melanie; El Kabbout, Reem; Yamamoto, Keiko; Martineau, Sandra; Pelletier, Andreanne; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Breuils-Bonnet, Sandra; Theberge, Charlie; Potus, Francois; Provencher, Steeve; Bonnet, Sebastien; Boucherat, Olivier Share Save
Narciclasine as a Novel Therapeutic Target for Pulmonary Arterial Hypertension: Addressing Glycosylation in Disease Pathophysiology Sleimen, Antonella Abi; El Kabbout, Reem; Bonnet, Sandra Breuils; Martineau, Sandra; Bourgeois, Alice; Sauvaget, Melanie; Romanet, Charlotte; Lemay, Sarah-Eve; Grobs, Yann; Boucherat, Olivier; Provencher, Steeve; Bonnet, Sebastien; Potus, Francois Share Save
Implication of Integrin α5β1 in right ventricular failure associated with pulmonary arterial hypertension Lemay, Sarah-Eve; Montesinos, Monica S.; Grobs, Yann; Theberge, Charlie; Sauvaget, Melanie; Yokokawa, Tetsuro; Shimauchi, Tsukasa; Romanet, Charlotte; Bourgeois, Alice; Breuils-Bonnet, Sandra; Martineau, Sandra; Dowling, James E.; Lu, Min; Saxena, Parmita; Mcteague, T. Andrew; Goodwin, Bryan; Lippa, Blaise; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
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