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Sphingosine kinase 2 (SphK2) depletion alters redox metabolism and enhances inflammation in a diet-induced MASH mouse model Jackson, Kaitlyn G.; Zhao, Derrick; Su, Lianyong; Lipp, Marissa K.; Toler, Cameron; Idowu, Michael; Yan, Qianhua; Wang, Xuan; Gurley, Emily; Wu, Nan; Puri, Puneet; Chen, Qun; Lesnefsky, Edward J.; Dupree, Jeffrey L.; Hylemon, Phillip B.; Zhou, Huiping Share Save
Metformin Therapy for Reperfusion Injury Consolidates Cardioprotection in the High-Risk Elderly Heart Rouhi, Nadiyeh; Wang, Hao; Nguyen, Jennie; Slotabec, Lily; Seale, Blaise; Wen, Changhong; Filho, Fernanda; Adenawoola, Michael; Chen, Qun; Lesnefsky, Edward; Li, Ji Share Save
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SPTLC3 Is Essential for Complex I Activity and Contributes to Ischemic Cardiomyopathy Kovilakath, Anna; Mauro, Adolfo G.; Valentine, Yolander A.; Raucci, Frank J.; Jamil, Maryam; Carter, Christiane; Thompson, Jeremy; Chen, Qun; Beutner, Gisela; Yue, Yang; Allegood, Jeremy; Wang, Xiaoxin X.; Dail, Jordan; Devarakonda, Teja; Myakala, Komuraiah; Windle, Jolene J.; Subler, Mark A.; Montefusco, David; Willard, Belinda; Javaheri, Ali; Bernas, Tytus; Mahata, Sushil K.; Levi, Moshe; Liu, Jinze; Porter, George A.; Lesnefsky, Edward J.; Salloum, Fadi N.; Cowart, L. Ashley Share Save
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Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential Meshrkey, Fibi; Scheulin, Kelly M.; Littlejohn, Christopher M.; Stabach, Joshua; Saikia, Bibhuti; Thorat, Vedant; Huang, Yimin; Laframboise, Thomas; Lesnefsky, Edward J.; Rao, Raj R.; West, Franklin D.; Iyer, Shilpa Share Save
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Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease Minowa, Kei; Rodriguez-Agudo, Daniel; Suzuki, Mitsuyoshi; Muto, Yamato; Hirai, Saeko; Wang, Yaping; Su, Lianyong; Zhou, Huiping; Chen, Qun; Lesnefsky, Edward J.; Mitamura, Kuniko; Ikegawa, Shigeo; Takei, Hajime; Nittono, Hiroshi; Fuchs, Michael; Pandak, William M.; Kakiyama, Genta Share Save
Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3 Iglesias, Migdalia; Wang, Hao; Krause-Hauch, Meredith; Ren, Di; Zoungrana, Linda Ines; Li, Zehui; Zhang, Jie; Wei, Jin; Yadav, Nikita; Patel, Kshama; Fatmi, Mohammad Kasim; Liu, Ruisheng; Lesnefsky, Edward J.; Li, Ji Share Save
Cardiomyocyte Pdk4 response is associated with metabolic maladaptation in aging Fatmi, Mohammad Kasim; Ren, Di; Fedorova, Julia; Zoungrana, Linda Ines; Wang, Hao; Davitt, Kayla; Li, Zehui; Iglesias, Migdalia; Lesnefsky, Edward J.; Krause-Hauch, Meredith; Li, Ji Share Save
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