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Karl Mechtler

vienna biocenter (vbc)

91H-index
390Paper Count
3.6WCitation Count
Published Papers 185
Publication Date
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Low-resolution FAIMS for increased peptide coverage in low-load and single-cell proteomics
errScientific Reports
IF3.9
err2026-03-01
err0
errOAAI
errHoch, Dominic G.; Belford, Michael; Heil, Lilian R.; Mechtler, Karl; Matzinger, Manuel
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errSave
Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma
errNature Communications
IF15.7
err2025-12-15
err0
errOAAI
errPranvera Sadiku; Alejandro J. Brenes; Rupert L. Mayer; Leila Reyes; Patricia Coelho; Gabi van Stralen; Ailiang Zhang; Manuel A. Sanchez-Garcia; Emily R. Watts; Imran Liaquat; Andrew J. M. Howden; Ikeoluwa Adekoya; Anuka Boldbaatar; Allan MacRaild; Sarah Risbridger; Gillian M. Morrison; Heather MacPherson; Caroline M. Bruce; Shonna Johnston; Robert Grecian; Fiona A. Murphy; Steven M. Pollard; Paul M. Brennan; Karl Mechtler; Sarah R. Walmsley
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errSave
Breaking barriers in crosslinking mass spectrometry with enhanced throughput and sensitivity using Orbitrap Astral
errNature Communications
IF15.7
err2025-11-10
err0
errOAAI
errFränze Müller; Micha J. Birklbauer; Julia Bubis; Karel Stejskal; Viktoria Dorfer; Karl Mechtler
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errSave
In vivo crosslinking and effective 2D enrichment for proteome wide interactome studies
errCommunications Chemistry
IF6.2
err2025-08-13
err0
errOAAI
errPhilipp Bräuer; Laszlo Tirian; Fränze Müller; Karl Mechtler; Manuel Matzinger
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errSave
Developing a new cleavable crosslinker reagent for in-cell crosslinking
errCommunications Chemistry
IF6.2
err2025-06-23
err0
errOAAI
errFränze Müller; Bogdan R. Brutiu; Iakovos Saridakis; Thomas Leischner; Micha J. Birklbauer; Manuel Matzinger; Mathias Madalinski; Thomas Lendl; Saad Shaaban; Viktoria Dorfer; Nuno Maulide; Karl Mechtler
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errSave
A Roadmap for Improving Reliability and Data Sharing in Crosslinking Mass Spectrometry
errMolecular & Cellular Proteomics
IF5.5
err2025-06-01
err0
errOAAI
errJuri Rappsilber; James Bruce; Colin Combe; Stephen D. Fried; Andrea Graziadei; Albert J.R. Heck; Claudio Iacobucci; Alexander Leitner; Karl Mechtler; Petr Novak; Francis O'Reilly; David C. Schriemer; Andrea Sinz; Florian Stengel; Konstantinos Thalassinos
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errSave
Proteome-wide non-cleavable crosslink identification with MS Annika 3.0 reveals the structure of the C. elegans Box C/D complex (vol 7,300,2024)
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2025-02-27
err0
errOAAI
errBirklbauer, Micha J.; Mueller, Fraenze; Geetha, Sowmya Sivakumar; Matzinger, Manuel; Mechtler, Karl; Dorfer, Viktoria
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errSave
A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2025-01-01
err0
PREAI
errChiva, Cristina; Olivella, Roger; Staes, An; Mendes Maia, Teresa; Panse, Christian; Stejskal, Karel; Douche, Thibaut; Lombard, Berangere; Schuhmann, Andrea; Loew, Damarys; Mechtler, Karl; Matondo, Mariette; Rettel, Mandy; Helm, Dominic; Impens, Francis; Devos, Simon; Shevchenko, Anna; Nanni, Paolo; Sabido, Eduard
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errSave
Proteome-wide non-cleavable crosslink identification with MS Annika 3.0 reveals the structure of the C. elegans Box C/D complex
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-12-19
err1
errOAAI
errBirklbauer, Micha J.; Mueller, Fraenze; Geetha, Sowmya Sivakumar; Matzinger, Manuel; Mechtler, Karl; Dorfer, Viktoria
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errSave
Identification of Pathogenic Pathways for Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation
errDIAGNOSTICS
IF3.3
err2024-07-24
err0
errOAAI
errPajenda, Sahra; Gerges, Daniela; Wagner, Ludwig; O'Connell, David; Aiad, Monika; Imre, Richard; Mechtler, Karl; Zimprich, Alexander; Schmidt, Alice; Sengoelge, Guerkan; Winnicki, Wolfgang
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errSave
Micropillar arrays, wide window acquisition and AI-based data analysis improve comprehensiveness in multiple proteomic applications
errNATURE COMMUNICATIONS
IF15.7
err2024-02-03
err7
errOAAI
errMatzinger, Manuel; Schmuecker, Anna; Yelagandula, Ramesh; Stejskal, Karel; Krssakova, Gabriela; Berger, Frederic; Mechtler, Karl; Mayer, Rupert L.
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errSave
A Causal Model of Ion Interference Enables Assessment and Correction of Ratio Compression in Multiplex Proteomics
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2024-01-01
err7
errOAAI
errMadern, Moritz; Reiter, Wolfgang; Stanek, Florian; Hartl, Natascha; Mechtler, Karl; Hartl, Markus
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errSave
A High-Sensitivity Low-Nanoflow LC-MS Configuration for High-Throughput Sample-Limited Proteomics
errANALYTICAL CHEMISTRY
IF6.7
err2023-12-13
err7
errOAAI
errZheng, Runsheng; Matzinger, Manuel; Mayer, Rupert L.; Valenta, Alec; Sun, Xuefei; Mechtler, Karl
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errSave
Immunopeptidomics in the Era of Single-Cell Proteomics
errBIOLOGY-BASEL
IF3.5
err2023-12-12
err7
errOAAI
errMayer, Rupert L.; Mechtler, Karl
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errSave
An Automated Nanowell-Array Workflow for Quantitative Multiplexed Single-Cell Proteomics Sample Preparation at High Sensitivity
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2023-12-01
err20
errOAAI
errCtortecka, Claudia; Hartlmayr, David; Seth, Anjali; Mendjan, Sasha; Tourniaire, Guilhem; Udeshi, Namrata D.; Carr, Steven A.; Mechtler, Karl
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errSave
Improving single cell proteomics experiments: how can we best utilize latest-generation data acquisition and MS instrument architecture?
errEXPERT REVIEW OF PROTEOMICS
IF2.8
err2023-09-24
err1
errOAAI
errMatzinger, Manuel; Mechtler, Karl
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errSave
MS Annika 2.0 Identifies Cross-Linked Peptides in MS2-MS3-Based Workflows at High Sensitivity and Specificity
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2023-08-11
err4
errOAAI
errBirklbauer, Micha J. J.; Matzinger, Manuel; Mueller, Fraenze; Mechtler, Karl; Dorfer, Viktoria
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errSave
The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
errNATURE COMMUNICATIONS
IF15.7
err2023-05-04
err5
errOAAI
errLackner, Andreas; Mueller, Michael; Gamperl, Magdalena; Stoeva, Delyana; Langmann, Olivia; Papuchova, Henrieta; Roitinger, Elisabeth; Duernberger, Gerhard; Imre, Richard; Mechtler, Karl; Latos, Paulina A. A.
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Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
errEMBO JOURNAL
IF8.3
err2023-04-04
err9
errOAAI
errSerebreni, Leonid; Pleyer, Lisa-Marie; Haberle, Vanja; Hendy, Oliver; Vlasova, Anna; Loubiere, Vincent; Nemcko, Filip; Bergauer, Katharina; Roitinger, Elisabeth; Mechtler, Karl; Stark, Alexander
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errSave
Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids
errELIFE
IF0
err2023-03-29
err13
errOAAI
errSidhaye, Jaydeep; Trepte, Philipp; Sepke, Natalie; Novatchkova, Maria; Schutzbier, Michael; Duernberger, Gerhard; Mechtler, Karl; Knoblich, Juergen A.
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Research Directions

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Co-authors
Cooperation Journals
J
Josef Penninger
H-index: 174 · Papers: 1.6K
S
Steven A. Carr
H-index: 152 · Papers: 987
R
Richard Durbin
H-index: 149 · Papers: 465
A
Al-BassamJawdat (Anthony A. Hyman)
H-index: 144 · Papers: 549
M
Michael Wagner
H-index: 141 · Papers: 566
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