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Bengt Westermark

Uppsala University
H-index:96
Citation Count:3.6万
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Targeting therapy-resistant SOX9-positive cells with a cytotoxic gene therapy in glioblastoma

使用细胞毒性基因疗法靶向治疗胶质母细胞瘤中具有治疗抵抗性的SOX9阳性细胞

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Vikstrom, Elin; Lin, Tong; Kissa, Eleftheria; Holmberg, Karl; Bergstrom, Tobias; Rosen, Gabriela; Badillo-Godinez, Oscar; Dalmo, Erika; Essand, Magnus; Westermark, Bengt; Hellstrom, Mats; Giraud, Geraldine; Rendo, Veronica; Swartling, Fredrik
p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

p21依赖的BMP4诱导衰老使胶质母细胞瘤细胞易受Senolytics影响

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
2025-04-230
OA
Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica; Westermark, Bengt
Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
SCIENTIFIC REPORTS
IF3.9
2024-01-094
OAAI
Gupta, Rajesh Kumar; Niklasson, Mia; Bergstroem, Tobias; Segerman, Anna; Betsholtz, Christer; Westermark, Bengt
Modeling glioblastoma heterogeneity as a dynamic network of cell states
MOLECULAR SYSTEMS BIOLOGY
IF7.7
2021-09-1623
OAAI
Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia; Doroszko, Milena; Segerman, Anna; Jornsten, Rebecka; Westermark, Bengt; Nelander, Sven
PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A
MOLECULAR ONCOLOGY
IF4.5
2021-07-166
OAAI
Tanabe, Ryo; Miyazono, Kohei; Todo, Tomoki; Saito, Nobuhito; Iwata, Caname; Komuro, Akiyoshi; Sakai, Satoshi; Raja, Erna; Koinuma, Daizo; Morikawa, Masato; Westermark, Bengt; Heldin, Carl-Henrik
A human cell type similar to murine central nervous system perivascular fibroblasts
EXPERIMENTAL CELL RESEARCH
IF3.5
2021-05-017
OAAI
Liu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe; Gustavsson, Sonja; Buyandelger, Byambajav; Vanlandewijck, Michael; Betsholtz, Christer; Westermark, Bengt; Andrae, Johanna
Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression
MOLECULAR CANCER RESEARCH
IF4.7
2020-07-0210
OAAI
Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida; Nelander, Sven; Westermark, Bengt
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
CELL DEATH & DISEASE
IF9.6
2019-11-2126
OAAI
Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara; Rosen, Gabriela; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene; Weishaupt, Holger; Swartling, Fredrik J.
Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

胶质母细胞瘤细胞的间质转化和治疗抵抗增加与星形胶质细胞反应性有关

JOURNAL OF PATHOLOGY
IF5.2
2019-08-3128
PREAI
Niklasson, Mia; Bergstrom, Tobias; Jarvius, Malin; Sundstrom, Anders; Nyberg, Frida; Haglund, Caroline; Larsson, Rolf; Westermark, Bengt; Segerman, Bo; Segerman, Anna
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
ONCOIMMUNOLOGY
IF6.3
2019-08-2287
OAAI
Kaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J.; Gabanic, Ben; Vega, Jose E. Velazquez; Shelton, Jennifer; Switchenko, Jeffrey M.; Ross, James L.; McSwain, Leon F.; Huse, Jason T.; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene; Maturi, Naga Prathyusha; Cimino, Patrick J.; Holland, Eric C.; Kettenmann, Helmut; Brennan, Cameron W.; Brat, Daniel J.; Hambardzumyan, Dolores
Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis
JOURNAL OF INTERNAL MEDICINE
IF9.2
2017-10-17134
OAAI
Heldin, C. -H.; Lennartsson, J.; Westermark, B.
Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3β expression and inhibition of STAT3 activation
CELLULAR SIGNALLING
IF3.7
2017-09-0143
PREAI
Attarha, Sanaz; Roy, Ananya; Westermark, Bengt; Tchougounova, Elena
Targeting of a mesenchymal profile in order to sensitize multitherapy resistant glioblastoma clones
CANCER RESEARCH
IF16.6
2017-07-011
PRE
Niklasson, Mia; Jarvius, Malin; Haglund, Caroline; Chantzi, Efthymia; Bergstrom, Tobias; Nyberg, Frida; Hermansson, Annika; Fryknas, Marten; Gustafsson, Mats; Segerman, Bo; Larsson, Rolf; Westermark, Bengt; Segerman, Anna
Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
CELL REPORTS
IF6.9
2016-12-01178
OAAI
Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergstrom, Tobias; Jarvius, Malin; Xie, Yuan; Westermark, Ann; Sonmez, Demet; Hermansson, Annika; Kastemar, Marianne; Naimaie-Ali, Zeinab; Nyberg, Frida; Berglund, Malin; Sundstrom, Magnus; Hesselager, Goran; Uhrbom, Lene; Gustafsson, Mats; Larsson, Rolf; Fryknas, Marten; Segerman, Bo; Westermark, Bengt
Origin of the U87MG glioma cell line: Good news and bad news
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2016-08-31356
PREAI
Allen, Marie; Bjerke, Mia; Edlund, Hanna; Nelander, Sven; Westermark, Bengt
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
SCIENTIFIC REPORTS
IF3.9
2016-07-2647
OAAI
Wee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena; Podlaha, Ondrej; Antczak, Christophe; Westermark, Bengt; Nelander, Sven; Uhrbom, Lene; Forsberg-Nilsson, Karin; Djaballah, Hakim; Michor, Franziska; Holland, Eric C.
GBM exhibits phenotypic microheterogeneity and harbors pre-existing multi resistant clones with a mesenchymal transition signature
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Segerman, Anna; Niklasson, Maria; Haglund, Caroline; Bergstrom, Tobias; Jarvius, Malin; Xie, Yuan; Simov, Demet Caglayan; Hermansson, Annika; Kastemar, Marianne; Naimaie-Ali, Zeinab; Berglund, Malin; Westermark, Ann; Sundstrom, Magnus; Hesselager, Goran; Uhrbom, Lene; Gustafsson, Mats; Larsson, Rolf; Fryknas, Marten; Segerman, Bo; Westermark, Bengt
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
CELL REPORTS
IF6.9
2016-01-01196
OAAI
Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia; Segerman, Anna; Flamourakis, Georgios; Fredriksson, Simon; Assarsson, Erika; Lundberg, Martin; Nelander, Sven; Westermark, Bengt; Landegren, Ulf
The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
EBIOMEDICINE
IF10.8
2015-10-01241
OAAI
Xie, Yuan; Bergstrom, Tobias; Jiang, Yiwen; Johansson, Patrik; Marinescu, Voichita Dana; Lindberg, Nanna; Segerman, Anna; Wicher, Grzegorz; Niklasson, Mia; Baskaran, Sathishkumar; Sreedharan, Smitha; Everlien, Isabelle; Kastemar, Marianne; Hermansson, Annika; Elfineh, Lioudmila; Libard, Sylwia; Holland, Eric Charles; Hesselager, Goran; Alafuzoff, Irina; Westermark, Bengt; Nelander, Sven; Forsberg-Nilsson, Karin; Uhrbom, Lene
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences
BMC GENOMICS
IF3.7
2015-05-165
OAAI
Agarwal, Prasoon; Collier, Paul; Fritz, Markus Hsi-Yang; Benes, Vladimir; Wiklund, Helena Jernberg; Westermark, Bengt; Singh, Umashankar

Research Directions

The data has not been retrieved yet.
L
Lene Uhrbom
H-index:35Papers:142Citations:4,268
M
Marianne Kastemar
H-index:14Papers:42Citations:1,552
A
Anna Segerman
H-index:14Papers:66Citations:1,627
S
Sven Nelander
H-index:36Papers:223Citations:6,119
T
Tobias Bergström
H-index:14Papers:85Citations:1,127
M
Mia Niklasson
H-index:10Papers:76Citations:1,102
M
Maria Ferletta
H-index:13Papers:29Citations:1,018
K
Karin Forsberg‐Nilsson
H-index:39Papers:219Citations:6,167
Y
Yiwen Jiang
H-index:19Papers:80Citations:1,443
U
Umashankar Singh
H-index:15Papers:59Citations:1,544