Jonathan K. Alder - Publications, H-index & Citations

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Jonathan K. Alder

university of pittsburgh

32H-index

130Paper Count

7.0KCitation Count

Published Papers 61

Publication Date

Accumulation of mucosal and lymphoid hypo-functional granzyme K producing CD8+ effector memory T cells in idiopathic pulmonary fibrosis

Mucosal Immunology

IF7.6

2026-07-17

PREAI

Jetina Okereke; Andrew Craig; Michelle Rojas; Blake Degioanni; Allyson Lieberman; John Sembrat; John Evankovich; William Bain; Harinath Bahudhanapati; Daniel J. Kass; Jonathan K. Alder; Mark E. Snyder

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Ligand-Independent Activation of Notch1 by Cathepsin L Induces CUX1/p16INK4a-Dependent Endothelial Senescence Associated With Atherosclerosis

Aging Cell

IF7.1

2026-05-28

OAAI

Yuwei Wu; Lili Lu; Shaoyang Yan; Zewen Du; Danli Jiang; Ting Wu; Qichao Wu; Jie Liu; Johny Ebin; Wei Sun; Partha Dutta; Jay Xiaojun Tan; Jonathan K. Alder; Gang Li

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ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation: Authors’ Perspective

the journal of heart and lung transplantation

IF0

2026-01-16

PREAI

Andrew M. Courtwright; John A. Mackintosh; Jonathan K. Alder; Christine Kim Garcia; Antoine Froidure; Erin Lowery; Don Hayes Jr.; Pali Shah; Quentin Philippot; Raphael Borie; John R. Greenland; Hannah Mannem; Mark E. Snyder; Merel Hellemons; Laurie D. Snyder; John McDyer

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ISHLT Consensus Statement on Short Telomere Syndrome and Lung Transplantation

the journal of heart and lung transplantation

IF0

2026-01-08

PREAI

Andrew M. Courtwright; John A. Mackintosh; Jonathan K. Alder; Christine Kim Garcia; Antoine Froidure; Erin Lowery; Don Hayes; Shah Pali; Quentin Philippot; Raphael Borie; John R. Greenland; Hannah Mannem; Mark E. Snyder; Merel Hellemons; Laurie D. Snyder; John McDyer

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Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic health

JCI Insight

IF6.1

2025-12-22

OAAI

Hernandez-Arciga, Ulalume; Kim, Jun Kyoung; Fisher, Jacob L.; Tyshkovskiy, Alexander; Moldakozhayev, Alibek; Hall, Catherine; Ghosh, Souvik; Govindaraj, Yashvandhini; Sipula, Ian J.; Kastroll, Jake; Cooke, Diana; Luo, Jinping; Alder, Jonathan K.; Rizzo, Stacey J. Sukoff; Ables, Gene P.; Choi, Eunhee; Gladyshev, Vadim N.; Jurczak, Michael J.; Tatar, Marc; Parkhitko, Andrey A.

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Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex

Nature Communications

IF15.7

2025-12-07

OAAI

Samantha L. Sanford; Mareike Badstübner; Michael Gerber; William Mannherz; Noah Lampl; Rachel Dannenberg; Angela Hinchie; Matthew A. Schaich; Sua Myong; Mark Hedglin; Suneet Agarwal; Jonathan K. Alder; Michael D. Stone; Patricia L. Opresko

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Genetic Variation in the Alternative Complement Pathway Contributes to Individual Susceptibility to Bacteremia and Sepsis

CRITICAL CARE EXPLORATIONS

IF2.7

2025-11-01

PREAI

Inman, Kyle; Chernus, Jonathan; Lee, Myoungkeun; Alder, Jonathan K.; Shah, Faraaz Ali; Mayr, Florian B.; Dempsey, Timothy; Nouraie, S. Mehdi; Dela Cruz, Charles; Ferreira, Viviana P.; Kulkarni, Hrishikesh S.; Meyer, Nuala J.; Strollo, Patrick J.; Feingold, Eleanor; Bain, William

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Belatacept as an alternative immunosuppressive agent for bone marrow-sparing in idiopathic pulmonary fibrosis lung transplant recipients with short telomeres

heart and lung transplantation

IF0

2025-05-07

PREAI

Stefanie J. Hannan; Carlo J. Iasella; Michel Sciullo; Cody Moore; Ryan Rivosecci; Lauren Sacha; Rachel M. Sutton; Ritchie Koshy; Norihisa Shigemura; Pablo G. Sanchez; Rafic Farah; Chadi A. Hage; Jonathan K. Alder; John F. McDyer

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Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner

SCIENCE ADVANCES

IF12.5

2025-04-18

PREAI

Hernandez-Arciga, Ulalume; Stamenkovic, Ceda; Yadav, Shweta; Nicoletti, Chiara; Albalawy, Wafaa N.; Al Hammood, Farazdaq; Gonzalez, Tiffany Fuentes; Naikwadi, Maitreyi U.; Graham, Aidan; Smarz, Christian; Little, Gabriela J.; Williams, Sean-Paul G.; Mcmahon, Brenda; Sipula, Ian J.; Vandevender, Amber M.; Chuan, Byron; Cooke, Diana; Pinto, Antonio F. M.; Flores, Lisa C.; Hartman, Hannah L.; Diedrich, Jolene K.; Brooke, Robert T.; Alder, Jonathan K.; Frahm, Krystle A.; Pascal, Laura E.; Stolt, Emma; Troensegaard, Hannibal; Ovrebo, Bente; Elshorbagy, Amany; Vinknes, Kathrine J.; Tan, Roderick J.; Weisz, Ora A.; Bueno, Marta; Eickelberg, Oliver; Steinhauser, Matthew L.; Finkel, Toren; Ables, Gene P.; Ikeno, Yuji; Sacco, Alessandra; Jurczak, Michael J.; Rizzo, Stacey J. Sukoff; Parkhitko, Andrey A.

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Skeletal muscle mitochondrial dysfunction is associated with increased Gdf15 expression and circulating GDF15 levels in aged mice

SCIENTIFIC REPORTS

IF3.9

2025-03-08

OAAI

Chen, J.; Kastroll, J.; Bello, F. M.; Pangburn, M. M.; Murali, A.; Smith, P. M.; Rychcik, K.; Loughridge, K. E.; Vandevender, A. M.; Dedousis, N.; Sipula, I. J.; Alder, J. K.; Jurczak, M. J.

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IL-10 Is Critical for Regulation of Cytotoxic CD4+NKG7+T Cells in Lung Allograft Rejection but Is Not Required for Allograft Acceptance

JOURNAL OF IMMUNOLOGY

IF3.4

2024-07-29

PREAI

Das, Antu; Wang, Xingan; Devonshire, Kaitlyn; Lyons, Emily J.; Popescu, Iulia; Zhou, Zihe; Li, Jingmei; Sembrat, John; Pilewski, Joseph; Zou, Chunbin; Alder, Jonathan K.; Chen, Bill B.; Snyder, Mark E.; McDyer, John F.

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A persistent variant telomere sequence in a human pedigree

NATURE COMMUNICATIONS

IF15.7

2024-06-01

OAAI

Hinchie, Angela M.; Sanford, Samantha L.; Loughridge, Kelly E.; Sutton, Rachel M.; Parikh, Anishka H.; Silva, Agustin A. Gil; Sullivan, Daniel I.; Chun-On, Pattra; Morrell, Matthew R.; McDyer, John F.; Opresko, Patricia L.; Alder, Jonathan K.

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Lung Epithelium Releases Growth Differentiation Factor 15 in Response to Pathogen-mediated Injury

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2024-05-01

OAAI

Shah, Faraaz A.; Bahudhanapati, Harinath; Jiang, Mao; Tabary, Mohammadreza; van der Geest, Rick; Tolman, Nathanial J.; Kochin, Megan; Xiong, Zeyu; Al-Yousif, Nameer; Sayed, Khaled; Benos, Panayiotis V.; Raffensperger, Kristen; Evankovich, John; Neal, Matthew D.; Snyder, Mark E.; Eickelberg, Oliver; Ray, Prabir; Dela Cruz, Charles; Bon, Jessica; McVerry, Bryan J.; Straub, Adam C.; Jurczak, Michael J.; Suber, Tomeka L.; Zhang, Yingze; Chen, Kong; Kitsios, Georgios D.; Lee, Janet S.; Alder, Jonathan K.; Bain, William G.

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Impact of age and telomere length on circulating T cells and rejection risk after lung transplantation for idiopathic pulmonary fibrosis

JOURNAL OF HEART AND LUNG TRANSPLANTATION

IF6

2023-12-01

OAAI

Snyder, Mark E.; Anderson, Michaela R.; Benvenuto, Luke J.; Sutton, Rachel M.; Bondonese, Anna; Koshy, Ritchie; Burke, Robin; Clifford, Sarah; Craig, Andrew; Iasella, Carlo J.; Hannan, Stefanie J.; Popescu, Iulia; Zhang, Yingze; Sanchez, Pablo G.; Alder, Jonathan K.; Mcdyer, John F.

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Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-11-02

PREAI

Bahudhanapati, Harinath; Tan, Jiangning; Apel, Rosa Marie; Seeliger, Benjamin; Schupp, Jonas; Li, Xiaoyun; Sullivan, Daniel I.; Sembrat, John; Rojas, Mauricio; Tabib, Tracy; Valenzi, Eleanor; Lafyatis, Robert; Mitash, Nilay; Pineda, Ricardo Hernandez; Jawale, Chetan; Peroumal, Doureradjou; Biswas, Partha; Tedrow, John; Adams, Taylor; Kaminski, Naftali; Wuyts, Wim A.; McDyer, John F.; Gibson, Kevin F.; Alder, Jonathan K.; Konigshoff, Melanie; Zhang, Yingze; Nouraie, Mehdi; Prasse, Antje; Kass, Daniel J.

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BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2023-11-01

OAAI

van der Geest, Rick; Penaloza, Hernan F.; Xiong, Zeyu; Gonzalez-Ferrer, Shekina; An, Xiaojing; Li, Huihua; Fan, Hongye; Tabary, Mohammadreza; Nouraie, S. Mehdi; Zhao, Yanwu; Zhang, Yingze; Chen, Kong; Alder, Jonathan K.; Bain, William G.; Lee, Janet S.

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LUNG TRANSPLANTATION FOR TELOMERE-MEDIATED PULMONARY FIBROSIS: EVIDENCE FOR SYSTEMIC DISEASE AND USING GENETICS TO ADVANCE PERSONALIZED MEDICINE

CHEST

IF8.6

2023-10-01

PREAI

McDyer, John F.; Hannan, Stefanie J.; Sutton, Rachel; Snyder, Mark E.; Iasella, Carlo J.; Hage, Chadi A.; Sanchez, Pablo G.; Popescu, Iulia; Alder, Jonathan K.

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Lung transplant recipients with telomere-mediated pulmonary fibrosis have increased risk for hematologic complications

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2023-10-01

PREAI

Hannan, Stefanie J.; Iasella, Carlo J.; Sutton, Rachel M.; Popescu, Iulia D.; Koshy, Ritchie; Burke, Robin; Chen, Xiaoping; Zhang, Yingze; Pilewski, Joseph M.; Hage, Chadi A.; Sanchez, Pablo G.; Im, Annie; Farah, Rafic; Alder, Jonathan K.; Mcdyer, John F.

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Intact mitochondrial function in the setting of telomere-induced senescence

AGING CELL

IF7.1

2023-09-08

OAAI

Sullivan, Daniel I.; Bello, Fiona M.; Silva, Agustin Gil; Redding, Kevin M.; Giordano, Luca; Hinchie, Angela M.; Loughridge, Kelly E.; Mora, Ana L.; Konigshoff, Melanie; Kaufman, Brett A.; Jurczak, Michael J.; Alder, Jonathan K.

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Spatial mapping of cellular senescence: emerging challenges and opportunities

NATURE AGING

IF19.4

2023-07-03

OAAI

Gurkar, Aditi U.; Gerencser, Akos A.; Mora, Ana L.; Nelson, Andrew C.; Zhang, Anru R.; Lagnado, Anthony B.; Enninful, Archibald; Benz, Christopher; Furman, David; Beaulieu, Delphine; Jurk, Diana; Thompson, Elizabeth L.; Wu, Fei; Rodriguez, Fernanda; Barthel, Grant; Chen, Hao; Phatnani, Hemali; Heckenbach, Indra; Chuang, Jeffrey H.; Horrell, Jeremy; Petrescu, Joana; Alder, Jonathan K.; Lee, Jun Hee; Niedernhofer, Laura J.; Kumar, Manoj; Konigshoff, Melanie; Bueno, Marta; Sokka, Miiko; Scheibye-Knudsen, Morten; Neretti, Nicola; Eickelberg, Oliver; Adams, Peter D.; Hu, Qianjiang; Zhu, Quan; Porritt, Rebecca A.; Dong, Runze; Peters, Samuel; Victorelli, Stella; Pengo, Thomas; Khaliullin, Timur; Suryadevara, Vidyani; Fu, Xiaonan; Bar-Joseph, Ziv; Ji, Zhicheng; Passos, Joao F.

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Research Directions