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Multiomics analysis of immune correlatives in hepatocellular carcinoma patients treated with tremelimumab plus durvalumab Myojin, Yuta; Babaei, Sepideh; Trehan, Rajiv; Hoffman, Christoph; Kedei, Noemi; Ruf, Benjamin; Benmebarek, Mohamed-Reda; Huang, Patrick; Ma, Chi; Monge, Cecilia; Xie, Changqing; Hrones, Donna; Duffy, Austin G.; Armstrong, Paul; Kocheise, Lorenz; Desmond, Fiona; Buchalter, Jemma; Galligan, Marie; Ryan, Ronan; Mccann, Jeff; Bourke, Michele; Mac Nicholas, Ross; Mcdermott, Ray; Awosika, Joy; Cam, Maggie; Krebs, Rosanna; Budhu, Anuradha; Revsine, Mahler; Figg, William D.; Kleiner, David E.; Redd, Bernadette; Wood, Bradford J.; Korangy, Firouzeh; Claassen, Manfred; Greten, Tim F. Share Save
Impairment of tumor reactive CD8 T cells in liver cancer Trehan, Rajiv S.; Soliman, Marlaine; Wang, Xin; Huang, Patrick; Kedei, Noemi; Zhu, Xiao Bin; Seifert, Matthias; Benmebarek, Mohamed-Reda; Nur, Amran; Korangy, Firouzeh; Ma, Chi; Greten, Tim F. Share Save
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Adenosine A2a receptor inhibition increases the anti-tumor efficacy of anti-PD1 treatment in murine hepatobiliary cancers Myojin, Yuta; McCallen, Justin D.; Ma, Chi; Bauer, Kylynda C.; Ruf, Benjamin; Benmebarek, Mohamed-Reda; Green, Benjamin L.; Wabitsch, Simon; McVey, John C.; Fu, Claude; Xie, Changqing; Greten, Tim F. Share Save
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy Lorenzini, Theo; Cadilha, Bruno L.; Obeck, Hannah; Benmebarek, Mohamed-Reda; Maerkl, Florian; Michaelides, Stefanos; Strzalkowski, Thaddaeus; Briukhovetska, Daria; Mueller, Philipp Jie; Nandi, Sayantan; Winter, Pia; Majed, Lina; Gruenmeier, Ruth; Seifert, Matthias; Rausch, Svenja; Feuchtinger, Tobias; Endres, Stefan; Kobold, Sebastian Share Save
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma Maerkl, Florian; Benmebarek, Mohamed-Reda; Keyl, Julius; Cadilha, Bruno L.; Geiger, Martina; Karches, Clara; Obeck, Hannah; Schwerdtfeger, Melanie; Michaelides, Stefanos; Briukhovetska, Daria; Stock, Sophia; Jobst, Jakob; Mueller, Philipp Jie; Majed, Lina; Seifert, Matthias; Kluever, Anna-Kristina; Lorenzini, Theo; Gruenmeier, Ruth; Thomas, Moritz; Gottschlich, Adrian; Klaus, Richard; Marr, Carsten; von Bergwelt-Baildon, Michael; Rothenfusser, Simon; Levesque, Mitchell P.; Heppt, Markus Vincent; Endres, Stefan; Klein, Christian; Kobold, Sebastian Share Save
Immune cell dynamics of patients and mice with hepatocellular carcinoma treated with anti-PD-L1 plus anti-CTLA-4 combination therapy Myojin, Yuta; Ruf, Benjamin; Benmebarek, Mohamed-Reda; Bauer, Kylynda; Trehan, Rajiv; Coffman, Kelley; Ma, Chi; Monge, Cecilia B.; Xie, Changqing; Greten, Tim Share Save
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten; Kobold, Sebastian Share Save
Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function Seifert, Matthias; Benmebarek, Mohamed-Reda; Briukhovetska, Daria; Maerkl, Florian; Doerr, Janina; Cadilha, Bruno L.; Jobst, Jakob; Stock, Sophia; Andreu-Sanz, David; Lorenzini, Theo; Gruenmeier, Ruth; Oner, Arman; Obeck, Hannah; Majed, Lina; Dhoqina, Dario; Feinendegen, Manouk; Gottschlich, Adrian; Zhang, Jin; Schindler, Ulrike; Endres, Stefan; Kobold, Sebastian Share Save
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors Stock, Sophia; Benmebarek, Mohamed-Reda; Kluever, Anna-Kristina; Darowski, Diana; Jost, Christian; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion; Endres, Stefan; Klein, Christian; Kobold, Sebastian Share Save
CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells Dezfouli, Ali Bashiri; Yazdi, Mina; Benmebarek, Mohamed-Reda; Schwab, Melissa; Michaelides, Stefanos; Micciche, Arianna; Geerts, Dirk; Stangl, Stefan; Klapproth, Sarah; Wagner, Ernst; Kobold, Sebastian; Multhoff, Gabriele Share Save
COMBINED PHARMACOLOGICAL TARGETING OF ADENOSINE 2A-AND 2B-RECEPTOR ENHANCES CAR T CELL FUNCTION Seifert, M.; Benmebarek, M.; Cadilha, B.; Jobst, J.; Doerr, J.; Lorenzini, T.; Dhoqina, D.; Zhang, J.; Zhang, J.; Schindler, U.; Endres, S.; Kobld, S. Share Save
A MODULAR AND CONTROLLABLE T CELL THERAPY PLATFORM FOR AML Benmebarek, M.; Cadilha, B. Loureiro; Herrmann, M.; Schmitt, S.; Lesch, S.; Stoiber, S.; Darwich, A.; Augsberger, C.; Brauchle, B.; Schwerdtfeger, M.; Gottschlich, A.; Rataj; Fenn, N. C.; Klein, C.; Subklewe, M.; Endres, S.; Hopfner, K.; Kobold, S. Share Save
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Dorman, Klara; Oner, Arman; Lorenzini, Theo; Obeck, Hannah; Vaenttinen, Mira; Di Pilato, Mauro; Pruessmann, Jasper N.; Stoiber, Stefan; Duc Huynh; Maerkl, Florian; Seifert, Matthias; Manske, Katrin; Suarez-Gosalvez, Javier; Zeng, Yi; Lesch, Stefanie; Karches, Clara H.; Heise, Constanze; Gottschlich, Adrian; Thomas, Moritz; Marr, Carsten; Zhang, Jin; Pandey, Dharmendra; Feuchtinger, Tobias; Subklewe, Marion; Mempel, Thorsten R.; Endres, Stefan; Kobold, Sebastian Share Save
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins Blaeschke, Franziska; Stenger, Dana; Apfelbeck, Antonia; Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Mahdawi, Jasmin; Ortner, Eva; Lepenies, Mareike; Habjan, Nicola; Rataj, Felicitas; Willier, Semjon; Kaeuferle, Theresa; Majzner, Robbie G.; Busch, Dirk H.; Kobold, Sebastian; Feuchtinger, Tobias Share Save
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours Lesch, Stefanie; Blumenberg, Viktoria; Stoiber, Stefan; Gottschlich, Adrian; Ogonek, Justyna; Cadilha, Bruno L.; Dantes, Zahra; Rataj, Felicitas; Dorman, Klara; Lutz, Johannes; Karches, Clara H.; Heise, Constanze; Kurzay, Mathias; Larimer, Benjamin M.; Grassmann, Simon; Rapp, Moritz; Nottebrock, Alessia; Kruger, Stephan; Tokarew, Nicholas; Metzger, Philipp; Hoerth, Christine; Benmebarek, Mohamed-Reda; Dhoqina, Dario; Grunmeier, Ruth; Seifert, Matthias; Oener, Arman; Umut, Oyku; Joaquina, Sandy; Vimeux, Lene; Tran, Thi; Hank, Thomas; Baba, Taisuke; Huynh, Duc; Megens, Remco T. A.; Janssen, Klaus-Peter; Jastroch, Martin; Lamp, Daniel; Ruehland, Svenja; Di Pilato, Mauro; Pruessmann, Jasper N.; Thomas, Moritz; Marr, Carsten; Ormanns, Steffen; Reischer, Anna; Hristov, Michael; Tartour, Eric; Donnadieu, Emmanuel; Rothenfusser, Simon; Duewell, Peter; Konig, Lars M.; Schnurr, Max; Subklewe, Marion; Liss, Andrew S.; Halama, Niels; Reichert, Maximilian; Mempel, Thorsten R.; Endres, Stefan; Kobold, Sebastian Share Save
A modular and controllable T cell therapy platform for acute myeloid leukemia Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter; Kobold, Sebastian Share Save
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CXCR6 EXPRESSION ENHANCES ACCUMULATION OF ANTI-MESOTHELIN CAR T CELLS AT THE TUMOR SITE AND THEIR THERAPEUTIC EFFICACY IN PANCREATIC CANCER XENOGRAFTS Stoiber, S.; Lesch, S.; Ogonek, J.; Cadilha, B.; Benmebarek, M.; Gottschlich, A.; Metzger, P.; Hoerth, C.; Nottebrock, A.; Endres, S.; Kobold, S. Share Save
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