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Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunity Sato, Naru; Goyama, Susumu; Chang, Yu-Hsuan; Miyawaki, Masashi; Fujino, Takeshi; Koide, Shuhei; Denda, Tamami; Liu, Xiaoxiao; Ueda, Koji; Yamamoto, Keita; Asada, Shuhei; Takeda, Reina; Yonezawa, Taishi; Tanaka, Yosuke; Honda, Hiroaki; Ota, Yasunori; Shibata, Takuma; Sekiya, Motohiro; Isobe, Tomoya; Lamagna, Chrystelle; Masuda, Esteban; Iwama, Atsushi; Shimano, Hitoshi; Inoue, Jun-ichiro; Miyake, Kensuke; Kitamura, Toshio Share Save
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Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells Punyawatthananukool, Siwakorn; Matsuura, Ryuma; Wongchang, Thamrong; Katsurada, Nao; Tsuruyama, Tatsuaki; Tajima, Masaki; Enomoto, Yutaka; Kitamura, Toshio; Kawashima, Masahiro; Toi, Masakazu; Yamanoi, Koji; Hamanishi, Junzo; Hisamori, Shigeo; Obama, Kazutaka; Charoensawan, Varodom; Thumkeo, Dean; Narumiya, Shuh Share Save
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HDAC7 is a potential therapeutic target in acute erythroid leukemia Zhang, Wenyu; Yamamoto, Keita; Chang, Yu-Hsuan; Yabushita, Tomohiro; Hao, Yangying; Shimura, Ruka; Nakahara, Jakushin; Shikata, Shiori; Iida, Kohei; Chen, Qianyi; Zhang, Xichen; Kitamura, Toshio; Goyama, Susumu Share Save
Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia Sugimoto, Emi; Li, Jingmei; Hayashi, Yasutaka; Iida, Kohei; Asada, Shuhei; Fukushima, Tsuyoshi; Tamura, Moe; Shikata, Shiori; Zhang, Wenyu; Yamamoto, Keita; Kawabata, Kimihito Cojin; Kawase, Tatsuya; Saito, Takeshi; Yoshida, Taku; Yamazaki, Satoshi; Kaito, Yuta; Imai, Yoichi; Denda, Tamami; Ota, Yasunori; Fukuyama, Tomofusa; Tanaka, Yosuke; Enomoto, Yutaka; Kitamura, Toshio; Goyama, Susumu Share Save
BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state Xiao, Muran; Kondo, Shinji; Nomura, Masaki; Kato, Shinichiro; Nishimura, Koutarou; Zang, Weijia; Zhang, Yifan; Akashi, Tomohiro; Viny, Aaron; Shigehiro, Tsukasa; Ikawa, Tomokatsu; Yamazaki, Hiromi; Fukumoto, Miki; Tanaka, Atsushi; Hayashi, Yasutaka; Koike, Yui; Aoyama, Yumi; Ito, Hiromi; Nishikawa, Hiroyoshi; Kitamura, Toshio; Kanai, Akinori; Yokoyama, Akihiko; Fujiwara, Tohru; Goyama, Susumu; Noguchi, Hideki; Lee, Stanley C.; Toyoda, Atsushi; Hinohara, Kunihiko; Abdel-Wahab, Omar; Inoue, Daichi Share Save
Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment Yabushita, Tomohiro; Chinen, Takumi; Nishiyama, Atsuya; Asada, Shuhei; Shimura, Ruka; Isobe, Tomoya; Yamamoto, Keita; Sato, Naru; Enomoto, Yutaka; Tanaka, Yosuke; Fukuyama, Tomofusa; Satoh, Hitoshi; Kato, Keiko; Saitoh, Kaori; Ishikawa, Takamasa; Soga, Tomoyoshi; Nannya, Yasuhito; Fukagawa, Tatsuo; Nakanishi, Makoto; Kitagawa, Daiju; Kitamura, Toshio; Goyama, Susumu Share Save
The E3 ligase DTX2 inhibits RUNX1 function by binding its C terminus and prevents the growth of RUNX1-dependent leukemia cells Yonezawa, Taishi; Takahashi, Hirotaka; Hao, Yangying; Furukawa, Chie; Tsuchiya, Akiho; Zhang, Wenyu; Fukushima, Tsuyoshi; Fukuyama, Tomofusa; Sawasaki, Tatsuya; Kitamura, Toshio; Goyama, Susumu Share Save
SETBP1 is dispensable for normal and malignant hematopoiesis Tanaka, Atsushi; Nishimura, Koutarou; Saika, Wataru; Kon, Ayana; Koike, Yui; Tatsumi, Hiromi; Takeda, June; Nomura, Masaki; Zang, Weijia; Nakayama, Manabu; Matsuda, Masashi; Yamazaki, Hiromi; Fukumoto, Miki; Ito, Hiromi; Hayashi, Yasutaka; Kitamura, Toshio; Kawamoto, Hiroshi; Takaori-Kondo, Akifumi; Koseki, Haruhiko; Ogawa, Seishi; Inoue, Daichi Share Save
TLR7/8 stress response drives histiocytosis in SLC29A3 disorders Shibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke Share Save
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Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia Urano, A; Endoh, M; Wada, T; Morikawa, Y; Itoh, M; Kataoka, Y; Taki, T; Akazawa, H; Nakajima, H; Komuro, I; Yoshida, N; Hayashi, Y; Handa, H; Kitamura, T; Nosaka, T Share Save
Mammalian twisted gastrulation is essential for skeleto-lymphogenesis Nosaka, T; Morita, S; Kitamura, H; Nakajima, H; Shibata, F; Morikawa, Y; Kataoka, Y; Ebihara, Y; Kawashima, T; Itoh, T; Ozaki, K; Senba, E; Tsuji, K; Makishima, F; Yoshida, N; Kitamura, T Share Save
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