Not logged inEngineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
Kast, Florian; Schwill, Martin; Stueber, Jakob C.; Pfundstein, Svende; Nagy-Davidescu, Gabriela; Rodriguez, Josep M. Monne; Seehusen, Frauke; Richter, Christian P.; Honegger, Annemarie; Hartmann, Karen Patricia; Weber, Thomas G.; Kroener, Felix; Ernst, Patrick; Piehler, Jacob; Pluckthun, Andreas .png)
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SaveComplexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonismDeluigi, Mattia; Klipp, Alexander; Klenk, Christoph; Merklinger, Lisa; Eberle, Stefanie A.; Morstein, Lena; Heine, Philipp; Mittl, Peer R. E.; Ernst, Patrick; Kamenecka, Theodore M.; He, Yuanjun; Vacca, Santiago; Egloff, Pascal; Honegger, Annemarie; Pluckthun, Andreas Share Save Share Save Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cellsBraciak, Todd A.; Roskopf, Claudia C.; Wildenhain, Sarah; Fenn, Nadja C.; Schiller, Christian B.; Schubert, Ingo A.; Jacob, Uwe; Honegger, Annemarie; Krupka, Christina; Subklewe, Marion; Spiekermann, Karsten; Hopfner, Karl-Peter; Fey, Georg H.; Aigner, Michael; Krause, Stefan; Mackensen, Andreas; Oduncu, Fuat S. Share Save Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune controlSchmid, Markus; Ernst, Patrick; Honegger, Annemarie; Suomalainen, Maarit; Zimmermann, Martina; Braun, Lukas; Stauffer, Sarah; Thom, Cristian; Dreier, Birgit; Eibauer, Matthias; Kipar, Anja; Vogel, Viola; Greber, Urs F.; Medalia, Ohad; Pluckthun, Andreas Share Save Share Save Share Save Share Save Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersDreier, Birgit; Honegger, Annemarie; Hess, Christian; Nagy-Davidescu, Gabriela; Mittl, Peer R. E.; Gruetter, Markus G.; Belousova, Natalya; Mikheeva, Galina; Krasnykh, Victor; Plueckthun, Andreas Share Save Share Save Share Save Share Save Share Save Share Save Share Save 
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