Not logged in A Phase 1b study of the OxPhos inhibitor ME-344 with bevacizumab in refractory metastatic colorectal cancer Boland, Patrick M.; Lenz, Heinz-Josef; Ciombor, Kristen K.; Florou, Vaia; Pishvaian, Michael J.; Cusnir, Michael; Cohen, Deirdre; Guo, Jessie Y.; Tang, Min; Rajagopalan, Prabhu; Wiley, Sandra E.; Ghalie, Richard G.; Hochster, Howard S. Share Save
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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro Hurrish, Katie H.; Su, Yongwei; Patel, Shraddha; Ramage, Cassandra L.; Zhao, Jianlei; Temby, Brianna R.; Carter, Jenna L.; Edwards, Holly; Buck, Steven A.; Wiley, Sandra E.; Huttemann, Maik; Polin, Lisa; Kushner, Juiwanna; Dzinic, Sijana H.; White, Kathryn; Bao, Xun; Li, Jing; Yang, Jay; Boerner, Julie; Hou, Zhanjun; Al-Atrash, Gheath; Konoplev, Sergej N.; Busquets, Jonathan; Tiziani, Stefano; Matherly, Larry H.; Taub, Jeffrey W.; Konopleva, Marina; Ge, Yubin; Baran, Natalia Share Save
Dual inhibition of HSF1 and DYRK2 impedes cancer Tandon, Vasudha; Moreno, Rita; Allmeroth, Kira; Quinn, Jean; Wiley, Sandra E.; Nicely, Lynden G.; Denzel, Martin S.; Edwards, Joanne; de la Vega, Laureano; Banerjee, Sourav Share Save
Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function Liu, Xiaoyan; Xiao, Weidi; Zhang, Yanan; Wiley, Sandra E.; Zuo, Tao; Zheng, Yingying; Chen, Natalie; Chen, Lu; Wang, Xiaorong; Zheng, Yawen; Huang, Lan; Lin, Shixian; Murphy, Anne N.; Dixon, Jack E.; Xu, Ping; Guo, Xing Share Save
Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression Banerjee, Sourav; Wei, Tiantian; Wang, Jue; Lee, Jenna J.; Gutierrez, Haydee L.; Chapman, Owen; Wiley, Sandra E.; Mayfield, Joshua E.; Tandon, Vasudha; Juarez, Edwin F.; Chavez, Lukas; Liang, Ruqi; Sah, Robert L.; Costello, Caitlin; Mesirov, Jill P.; de la Vega, Laureano; Cooper, Kimberly L.; Dixon, Jack E.; Xiao, Junyu; Lei, Xiaoguang Share Save
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure Pollak, Adam J.; Liu, Canzhao; Gudlur, Aparna; Mayfield, Joshua E.; Dalton, Nancy D.; Gu, Yusu; Chen, Ju; Brown, Joan Heller; Hogan, Patrick G.; Wiley, Sandra E.; Peterson, Kirk L.; Dixon, Jack E. Share Save
Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide Qiu, Yimin; Poppleton, Erik; Mekkat, Arya; Yu, Hongtao; Banerjee, Sourav; Wiley, Sandra E.; Dixon, Jack E.; Kaplan, David L.; Lin, Yu-Shan; Brodsky, Barbara Share Save
Phosphorylation of serine96 of histidine-rich calcium- binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia Pollak, Adam J.; Haghighi, Kobra; Kunduri, Swati; Arvanitis, Demetrios A.; Bidwell, Philip A.; Liu, Guan-Sheng; Singh, Vivek P.; Gonzalez, David J.; Sanoudou, Despina; Wiley, Sandra E.; Dixon, Jack E.; Kranias, Evangelia G. Share Save
Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function Yamazaki, Katrina Go; Andreyev, Aleksander Y.; Ortiz-Vilchis, Pilar; Petrosyan, Susanna; Divakaruni, Ajit S.; Wiley, Sandra E.; De la Fuente, Christine; Perkins, Guy; Ceballos, Guillermo; Villarreal, Francisco; Murphy, Anne N. Share Save
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis Tagliabracci, Vincent S.; Engel, James L.; Wiley, Sandra E.; Xiao, Junyu; Gonzalez, David J.; Appaiah, Hitesh Nidumanda; Koller, Antonius; Nizet, Victor; White, Kenneth E.; Dixon, Jack E. Share Save
Cellular and bioenergetic dysfunction induced by loss of the Wolfram Syndrome protein, Miner1, can be reversed by treatment with N-acetylcysteine Wiley, Sandra E.; Andreyev, Alexander Y.; Divakaruni, Ajit S.; Karisch, Robert; Perkins, Guy; van der Geer, Peter; Tsai, Ting-Fen; Simon, Melvin I.; Neel, Benjamin G.; Dixon, Jack E.; Murphy, Anne N. Share Save
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Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+homeostasis Wiley, Sandra E.; Andreyev, Alexander Y.; Divakaruni, Ajit S.; Karisch, Robert; Perkins, Guy; Wall, Estelle A.; van der Geer, Peter; Chen, Yi-Fan; Tsai, Ting-Fen; Simon, Melvin I.; Neel, Benjamin G.; Dixon, Jack E.; Murphy, Anne N. Share Save
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier Divakaruni, Ajit S.; Wiley, Sandra E.; Rogers, George W.; Andreyev, Alexander Y.; Petrosyan, Susanna; Loviscach, Mattias; Wall, Estelle A.; Yadava, Nagendra; Heuck, Alejandro P.; Ferrick, David A.; Henry, Robert R.; McDonald, William G.; Colca, Jerry R.; Simon, Melvin I.; Ciaraldi, Theodore P.; Murphy, Anne N. Share Save
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Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis Zhang, Ji; Guan, Ziqiang; Murphy, Anne N.; Wiley, Sandra E.; Perkins, Guy A.; Worby, Carolyn A.; Engel, James L.; Heacock, Philip; Oanh Kim Nguyen; Wang, Jonathan H.; Raetz, Christian R. H.; Dowhan, William; Dixon, Jack E. Share Save
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MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone Paddock, Mark L.; Wiley, Sandra E.; Axelrod, Herbert L.; Cohen, Aina E.; Roy, Melinda; Abresch, Edward C.; Capraro, Dominique; Murphy, Anne N.; Nechushtai, Rachel; Dixon, Jack E.; Jennings, Patricia A. Share Save
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