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GNAS mutation inhibits growth and induces phosphodiesterase 4D expression in colorectal cancer cell lines Nummela, Pirjo; Zafar, Sadia; Veikkolainen, Erika; Ukkola, Iiris; Cinella, Vincenzo; Ayo, Abiodun; Asghar, Muhammad Yasir; Valimaki, Niko; Tornquist, Kid; Karhu, Auli; Laakkonen, Pirjo; Aaltonen, Lauri A.; Ristimaki, Ari Share Save
Genome-Wide Association Study Identifies 4 Novel Risk Loci for Small Intestinal Neuroendocrine Tumors Including a Missense Mutation in LGR5 Giri, Anil K.; Aavikko, Mervi; Wartiovaara, Linnea; Lemmetyinen, Toni; Karjalainen, Juha; Mehtonen, Juha; Palin, Kimmo; Valimaki, Niko; Tamlander, Max; Saikkonen, Riikka; Karhu, Auli; Morgunova, Ekaterina; Sun, Benjamin; Runz, Heiko; Palta, Priit; Luo, Shuang; Joensuu, Heikki; Makela, Tomi P.; Kostiainen, Iiro; Schalin-Jantti, Camilla; FinnGen; Palotie, Aarno; Aaltonen, Lauri A.; Ollila, Saara; Daly, Mark J. Share Save
The clinical and therapeutic profiles of prolactinomas associated with germline pathogenic variants in the aryl hydrocarbon receptor interacting protein (AIP) gene Vroonen, Laurent; Beckers, Albert; Camby, Severine; Cuny, Thomas; Beckers, Pablo; Jaffrain-Rea, Marie-Lise; Cogne, Muriel; Naves, Luciana; Ferriere, Amandine; Romanet, Pauline; Elenkova, Atanaska; Karhu, Auli; Brue, Thierry; Barlier, Anne; Petrossians, Patrick; Daly, Adrian F. Share Save
Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas Valimaki, Niko; Jokinen, Vilja; Cajuso, Tatiana; Kuisma, Heli; Taira, Aurora; Dagnaud, Olivia; Ilves, Sini; Kaukomaa, Jaana; Pasanen, Annukka; Palin, Kimmo; Heikinheimo, Oskari; Butzow, Ralf; Aaltonen, Lauri A.; Karhu, Auli Share Save
Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate Kolterud, Asa; Valimaki, Niko; Kuisma, Heli; Patomo, Joonatan; Ilves, Sini T.; Makinen, Netta; Kaukomaa, Jaana; Palin, Kimmo; Kaasinen, Eevi; Karhu, Auli; Pasanen, Annukka; Butzow, Ralf; Heikinheimo, Oskari; Kallner, Helena Kopp; Aaltonen, Lauri A. Share Save
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Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans Kaasinen, Eevi; Kuismin, Outi; Rajamaki, Kristiina; Ristolainen, Heikki; Aavikko, Mervi; Kondelin, Johanna; Saarinen, Silva; Berta, Davide G.; Katainen, Riku; Hirvonen, Elina A. M.; Karhu, Auli; Taira, Aurora; Tanskanen, Tomas; Alkodsi, Amjad; Taipale, Minna; Morgunova, Ekaterina; Franssila, Kaarle; Lehtonen, Rainer; Makinen, Markus; Aittomaki, Kristiina; Palotie, Aarno; Kurki, Mitja, I; Pietilainen, Olli; Hilpert, Morgane; Saarentaus, Elmo; Niinimaki, Jaakko; Junttila, Juhani; Kaikkonen, Kari; Vahteristo, Pia; Skoda, Radek C.; Seppanen, Mikko R. J.; Eklund, Kari K.; Taipale, Jussi; Kilpivaara, Outi; Aaltonen, Lauri A. Share Save
Global metabolomic profiling of uterine leiomyomas Heinonen, Hanna-Riikka; Mehine, Miika; Makinen, Netta; Pasanen, Annukka; Pitkanen, Esa; Karhu, Auli; Sarvilinna, Nanna S.; Sjoberg, Jari; Heikinheimo, Oskari; Butzow, Ralf; Aaltonen, Lauri A.; Kaasinen, Eevi Share Save
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Mild pituitary phenotype in 3-and 12-month-old Aip-deficient male mice Lecoq, Anne-Lise; Zizzari, Philippe; Hage, Mirella; Decourtye, Lyvianne; Adam, Clovis; Viengchareun, Say; DVeldhuis, Johannes; Geoffroy, Valerie; Lombes, Marc; Tolle, Virginie; Guillou, Anne; Karhu, Auli; Kappeler, Laurent; Chanson, Philippe; Kamenicky, Peter Share Save
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Aryl hydrocarbon receptor interacting protein mutations seem not to associate with familial non-medullary thyroid cancer Raitila, A.; Georgitsi, M.; Bonora, E.; Vargiolu, M.; Tuppurainen, K.; Makinen, M. J.; Vierimaa, O.; Salmela, P. I.; Launonen, V.; Vahteristo, P.; Aaltonen, L. A.; Romeo, G.; Karhu, A. Share Save
AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling Tuominen, I.; Heliovaara, E.; Raitila, A.; Rautiainen, M-R; Mehine, M.; Katainen, R.; Donner, I.; Aittomaki, V.; Lehtonen, H. J.; Ahlsten, M.; Kivipelto, L.; Schalin-Jantti, C.; Arola, J.; Hautaniemi, S.; Karhu, A. Share Save
Identification of Candidate Oncogenes in Human Colorectal Cancers With Microsatellite Instability Gylfe, Alexandra E.; Kondelin, Johanna; Turunen, Mikko; Ristolainen, Heikki; Katainen, Riku; Pitkanen, Esa; Kaasinen, Eevi; Rantanen, Ville; Tanskanen, Tomas; Varjosalo, Markku; Lehtonen, Heli; Palin, Kimmo; Taipale, Minna; Taipale, Jussi; Renkonen-Sinisalo, Laura; Jarvinen, Heikki; Bohm, Jan; Mecklin, Jukka-Pekka; Ristimaki, Ari; Kilpivaara, Outi; Tuupanen, Sari; Karhu, Auli; Vahteristo, Pia; Aaltonen, Lauri A. Share Save
Candidate driver genes in microsatellite-unstable colorectal cancer Alhopuro, Pia; Sammalkorpi, Heli; Niittymaki, Iina; Bistrom, Mia; Raitila, Anniina; Saharinen, Juha; Nousiainen, Kari; Lehtonen, Heli J.; Heliovaara, Elina; Puhakka, Jani; Tuupanen, Sari; Sousa, Sonia; Seruca, Raquel; Ferreira, Ana M.; Hofstra, Robert M. W.; Mecklin, Jukka-Pekka; Jarvinen, Heikki; Ristimaki, Ari; Orntoft, Torben F.; Hautaniemi, Sampsa; Arango, Diego; Karhu, Auli; Aaltonen, Lauri A. Share Save
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High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint Niittymaki, Iina; Gylfe, Alexandra; Laine, Leena; Laakso, Marko; Lehtonen, Heli J.; Kondelin, Johanna; Tolvanen, Jaana; Nousiainen, Kari; Pouwels, Jeroen; Jarvinen, Heikki; Nuorva, Kyosti; Mecklin, Jukka-Pekka; Makinen, Markus; Ristimaki, Ari; Orntoft, Torben F.; Hautaniemi, Sampsa; Karhu, Auli; Kallio, Marko J.; Aaltonen, Lauri A. Share Save
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